Enalaprilat
66 interactions 1 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 10, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Aliskiren
Allopurinol
Allopurinol Injection
Melphalan
Cyclosporine Ophthalmic
Methotrexate Injection
Contraindicated
Enalaprilat Aliskiren Tekturna An increased risk of hyperkalemia, renal impairment, and hypotension DetailsMajor
Enalaprilat Allopurinol Aloprim Hypersensitivity reactions (Stevens-Johnson syndrome, skin eruptions, anaphylactic coronary spasm) Details Enalaprilat Allopurinol Injection Aloprim Hypersensitivity reactions (Stevens-Johnson syndrome, skin eruptions, anaphylactic coronary spasm) Details Enalaprilat Aspirin Acuprin® Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Enalaprilat Aspirin Rectal Aspirin Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Enalaprilat Azathioprine Azasan An increased risk of myelosuppression and an increased risk of hepatotoxicity Details Enalaprilat Azilsartan Edarbi Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalaprilat Cyclosporine Injection Atopica Acute renal dysfunction and an increased risk of hyperkalemia Details Enalaprilat Cyclosporine Ophthalmic Cequa Acute renal dysfunction and an increased risk of hyperkalemia Details Enalaprilat Digoxin Cardoxin® An increased digoxin exposure Details Enalaprilat Eprosartan Teveten® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalaprilat Everolimus Afinitor Increased risk of angioedema Details Enalaprilat Furosemide Injection Disal An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Enalaprilat Irbesartan Avapro Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalaprilat Lithium Carbonate Lithobid Increased risk of lithium toxicity Details Enalaprilat Losartan Arbli Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalaprilat Melphalan Alkeran An increased risk of severe hypotension Details Enalaprilat Melphalan Injection Alkeran An increased risk of severe hypotension Details Enalaprilat Mercaptopurine Purinethol® An increased risk of myelosuppression and an increased risk of hepatotoxicity Details Enalaprilat Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Enalaprilat Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... DetailsModerate
Enalaprilat Acarbose Prandase® Explained An increased risk of hypoglycemia Details Enalaprilat Asenapine Transdermal Patch Secuado An increased risk of hypotension Details Enalaprilat Alogliptin Nesina An increased risk of hypoglycemia Details Enalaprilat Bromfenac Ophthalmic Bromday® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Enalaprilat Canagliflozin Invokana An increased risk of hypoglycemia Details Enalaprilat Capsaicin Arthricare for Women Moisturizing Increased risk of cough Details Enalaprilat Capsaicin Topical Aspercreme Warming® Increased risk of cough Details Enalaprilat Capsaicin Transdermal Patch Aspercreme Warming® Patch Increased risk of cough Details Enalaprilat Dapagliflozin Farxiga An increased risk of hypoglycemia Details Enalaprilat Diclofenac Ophthalmic Voltaren® Eye Drops Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Enalaprilat Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Enalaprilat Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Enalaprilat Diclofenac Transdermal Patch Flector Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Enalaprilat Dulaglutide Injection Trulicity An increased risk of hypoglycemia Details Enalaprilat Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) An increased risk of hypoglycemia Details Enalaprilat Ertugliflozin Steglatro An increased risk of hypoglycemia Details Enalaprilat Etodolac Lodine Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Enalaprilat Exenatide Injection Bydureon An increased risk of hypoglycemia Details Enalaprilat Fenoprofen Fenopron Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
Check another drug
Still have questions about this combination?
Every question gets a real answer from a licensed pharmacist — free, and usually within a day.
Ask the pharmacistEducational information only, not medical advice. Always confirm interactions with your pharmacist
or prescriber before making any change to your medications.