Phenylpropanolamine
7 interactions
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Aug 8, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Dihydroergotamine Injection
Dihydroergotamine Nasal Spray
Linezolid Injection
Anagrelide
Fentanyl Transdermal Patch
Hydroxychloroquine
Contraindicated
Phenylpropanolamine Dihydroergotamine Injection DHE-45® Injection Extreme elevation of blood pressure Details Phenylpropanolamine Dihydroergotamine Nasal Spray Migranal Extreme elevation of blood pressure Details Phenylpropanolamine Linezolid Injection Zyvox An increase in blood pressure DetailsMajor
Phenylpropanolamine Anagrelide Agrylin Increased anagrelide exposure Details Phenylpropanolamine Fentanyl Transdermal Patch Duragesic® Reduced analgesic effect Details Phenylpropanolamine Hydroxychloroquine Plaquenil An increased risk of seizures DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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