Betaxolol

188 interactions 1 explained in plain English 395 cited references
Also sold as: Betoptic S Kerlone®
About Betaxolol

Betaxolol is a beta blocker used to control high blood pressure. Read the full Betaxolol drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Betaxolol Albuterol Oral Inhalation Accuneb® Explained Reduced efficacy of albuterol Details Betaxolol Albuterol ProAir Reduced efficacy of albuterol Details Betaxolol Ceritinib Zykadia Increased risk of bradycardia Details Betaxolol Clonidine Duraclon An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Betaxolol Crizotinib Xalkori An increased risk of bradycardia Details Betaxolol Darunavir Increased beta blocker exposure and an increased risk of beta blocker-related adverse effects Details Betaxolol Diltiazem Cardizem An increased risk of hypotension, bradycardia and slow AV conduction Details Betaxolol Disopyramide Norpace Severe bradycardia, asystole and heart failure Details Betaxolol Dronedarone Multaq Increased exposure to some beta blockers and increased incidence of bradycardia Details Betaxolol Epinephrine Antagonized cardio stimulating and bronchodilation effects of EPINEPHrine, an increased risk of severe hypertension and an increas... Details Betaxolol Fenoldopam Exaggeration of hypotensive response Details Betaxolol Fingolimod Gilenya Slowing of the heart rate or atrioventricular conduction, which may result in severe bradycardia or heart block Details Betaxolol Formoterol Perforomist Reduced efficacy of formoterol or reduced efficacy of beta-adrenergic blocker Details Betaxolol Indacaterol Decreased efficacy of indacaterol Details Betaxolol Insulin Afrezza Increased or reduced blood glucose lowering effect of insulin and reduced symptoms of hypoglycemia Details Betaxolol Insulin Icodec-Abae Awiqli An increased risk of hypoglycemia, which may sometimes be followed by hyperglycemia and an increased risk of blunted recognition o... Details Betaxolol Iohexol Lower threshold for contrast reactions, increased risk of more severe contrast reaction, reduced efficacy when treating hypersensi... Details Betaxolol Lacosamide Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Betaxolol Landiolol An increased risk of myocardial contractility depression and increase the risk of bradycardia or heart block Details Betaxolol Levalbuterol Xopenex Reduced efficacy of levalbuterol Details Betaxolol Melatonin An increased risk of suppression of endogenous melatonin levels Details Betaxolol Methylergonovine Methergine An increased risk of enhanced vasoconstrictive Details Betaxolol Olodaterol Striverdi Reduced olodaterol exposure and reduced beta-adrenergic blockers exposure Details Betaxolol Phenelzine Nardil An increased risk of exaggerated hypotensive effect and an increased risk of bradycardia Details Betaxolol Ponesimod Ponvory An increased risk of severe bradycardia and heart block Details Betaxolol Rivastigmine Exelon Additive bradycardic effects Details Betaxolol Salmeterol Serevent Reduced efficacy of salmeterol Details Betaxolol Siponimod Mayzent An increased risk of severe bradycardia and heart block Details Betaxolol Terbutaline Brethine® Reduced efficacy of terbutaline Details Betaxolol Verapamil Calan An increased risk of hypotension, bradycardia and slow AV conduction Details Betaxolol Vilanterol Decreased efficacy of vilanterol Details Betaxolol Clonidine Transdermal Patch Catapres An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Betaxolol Indacaterol Oral Inhalation Arcapta® Decreased efficacy of indacaterol Details Betaxolol Lacosamide Injection Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Betaxolol Olodaterol Oral Inhalation Striverdi Reduced olodaterol exposure and reduced beta-adrenergic blockers exposure Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.