Selumetinib
18 interactions 1 explained in plain EnglishSelumetinib is used to treat neurofibromatosis type 1 (NF1; a nervous system disorder that causes tumors to grow on nerves) in children 2 years of age and older who have plexiform neurofibromas (PN; soft tumors) that cannot be completely removed by surgery. Selumetinib is in a class of medications called kinase inhibit… Read the full Selumetinib drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Selumetinib Abametapir Explained Increased exposure of CYP3A4 substrate Details Selumetinib Aspirin Acuprin® Increased risk of bleeding Details Selumetinib Aspirin Rectal Aspirin Increased risk of bleeding Details Selumetinib Anagrelide Agrylin Increased risk of bleeding Details Selumetinib Clopidogrel Plavix Increased risk of bleeding Details Selumetinib Dexamethasone Injection Decadron Reduced selumetinib exposure and reduced efficacy of selumetinib Details Selumetinib Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced selumetinib exposure and reduced efficacy of selumetinib Details Selumetinib Dipyridamole Permole® Increased risk of bleeding Details Selumetinib Encorafenib Braftovi Reduced selumetinib exposure and reduced efficacy of selumetinib Details Selumetinib Epoprostenol Flolan Increased risk of bleeding Details Selumetinib Iloprost Aurlumyn Increased risk of bleeding Details Selumetinib Ketoconazole Topical Extina® Foam Increased selumetinib exposure and an increased risk of selumetinib-related adverse reactions Details Selumetinib Lefamulin Xenleta Increased selumetinib exposure and an increased risk of selumetinib-related adverse reactions Details Selumetinib Lenacapavir Injection Sunlenca Increased selumetinib exposure and an increased risk of selumetinib-related adverse reactions Details Selumetinib Lenacapavir Oral Sunlenca Increased selumetinib exposure and an increased risk of selumetinib-related adverse reactions Details Selumetinib Letermovir Injection Prevymis Increased selumetinib exposure and an increased risk of selumetinib-related adverse reactions Details Selumetinib Mitapivat Aqvesme Reduced selumetinib exposure and reduced efficacy of selumetinib Details Selumetinib Nafcillin Injection Unipen® Injection Reduced selumetinib exposure and reduced efficacy of selumetinib DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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