Penicillamine

Name: Penicillamine Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

2 interactions

Also sold as: Aagylur Cupramine® Cuprimine Depen Depen®

About Penicillamine

Penicillamine is used to treat Wilson's disease (an inherited condition that causes copper to build up in the body and may result in serious symptoms) and cystinuria (an inherited condition which can lead to kidney stones). It is also used in combination with other treatments to treat severe rheumatoid arthritis (a con… Read the full Penicillamine drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Auranofin Digoxin

2 Major

All (2) Major (2)

Major

Penicillamine Auranofin Ridaura Increased bone marrow depression, rash Details Penicillamine Digoxin Cardoxin® Reduced digoxin exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.