Tenofovir Alafenamide
67 interactions 1 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 10, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Acyclovir
Acyclovir Injection
Capmatinib
Bromfenac Ophthalmic
Aspirin
Gentamicin Injection
Major
Tenofovir Alafenamide Acyclovir Avaclyr Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Acyclovir Injection Avaclyr Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Acyclovir Ophthalmic Avaclyr Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Acyclovir Topical Zovirax Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Amikacin Injection Amikin® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Amikacin Oral Inhalation Arikayce Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Asciminib Scemblix Increased BCRP substrate exposure and an increased risk of BCRP substrate-related adverse effects Details Tenofovir Alafenamide Aspirin Acuprin® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Aspirin Rectal Aspirin Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Bromfenac Ophthalmic Bromday® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Capmatinib Tabrecta Risk of increased adverse reactions Details Tenofovir Alafenamide Cidofovir Injection Vistide® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Darolutamide Nubeqa Increased plasma concentrations of BCRP substrates Details Tenofovir Alafenamide Diclofenac Ophthalmic Voltaren® Eye Drops Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Diclofenac Topical (Actinic Keratosis) Pennsaid Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Diclofenac Topical (Arthritis Pain) Pennsaid® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Diclofenac Transdermal Patch Flector Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Enasidenib Idhifa Increased exposure of BCRP substrate Details Tenofovir Alafenamide Etodolac Lodine Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Febuxostat Uloric Increased tenofovir alafenamide exposure Details Tenofovir Alafenamide Fenoprofen Fenopron Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Flurbiprofen Ansaid Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Flurbiprofen Ophthalmic Ocufen Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Fostemsavir Rukobia Increased tenofovir alafenamide exposure Details Tenofovir Alafenamide Ganciclovir Cytovene® Oral Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Ganciclovir Injection Cytovene® I.V.® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Ganciclovir Ophthalmic Zirgan Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Gentamicin Injection Garamycin® I.V. Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Gentamicin Ophthalmic Garamycin® Ophthalmic Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Gentamicin Topical Garamycin® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Ibuprofen Addaprin Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Ketoprofen Actron® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Ketorolac Acular Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Ketorolac Injection Acular Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Ketorolac Nasal Spray Sprix Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Ketorolac Ophthalmic Acular Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Leflunomide Arava Increased exposure of BCRP substrate Details Tenofovir Alafenamide Leniolisib Joenja Increased BCRP substrate exposure Details Tenofovir Alafenamide Meclofenamate Meclodium® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Tenofovir Alafenamide Mefenamic Acid Ponstel® Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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