Spirapril

Major

Spirapril Aspirin Acuprin® Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Spirapril Aspirin Rectal Aspirin Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Spirapril Azathioprine Azasan Myelosuppression Details Spirapril Azilsartan Edarbi Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Spirapril Cyclosporine Injection Atopica Acute renal dysfunction and an increased risk of hyperkalemia Details Spirapril Cyclosporine Ophthalmic Cequa Acute renal dysfunction and an increased risk of hyperkalemia Details Spirapril Digoxin Cardoxin® An increased digoxin exposure Details Spirapril Eprosartan Teveten® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Spirapril Everolimus Afinitor An increased risk of angioedema Details Spirapril Furosemide Injection Disal An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Spirapril Irbesartan Avapro Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Spirapril Lithium Carbonate Lithobid Increased risk of lithium toxicity Details Spirapril Losartan Arbli Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Spirapril Mercaptopurine Purinethol® Myelosuppression Details

Moderate

Spirapril Asenapine Transdermal Patch Secuado An increased risk of hypotension Details Spirapril Bromfenac Ophthalmic Bromday® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Capsaicin Arthricare for Women Moisturizing Increased risk of cough Details Spirapril Capsaicin Topical Aspercreme Warming® Increased risk of cough Details Spirapril Capsaicin Transdermal Patch Aspercreme Warming® Patch Increased risk of cough Details Spirapril Diclofenac Ophthalmic Voltaren® Eye Drops Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Diclofenac Transdermal Patch Flector Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Etodolac Lodine Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Fenoprofen Fenopron Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Flurbiprofen Ansaid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Flurbiprofen Ophthalmic Ocufen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Ibuprofen Addaprin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Ketoprofen Actron® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Ketorolac Acular Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Ketorolac Injection Acular Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Ketorolac Nasal Spray Sprix Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Ketorolac Ophthalmic Acular Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Meclofenamate Meclodium® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Mefenamic Acid Ponstel® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Meloxicam Alloxate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Meloxicam Injection Alloxate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Nabumetone Relafen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Spirapril Naproxen Aleve Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details