Istradefylline

Contraindicated

Istradefylline Colchicine Colcrys Increased colchicine exposure and an increased risk of fatal toxicity Details Istradefylline Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details

Major

Istradefylline Abametapir Increased exposure of CYP3A4 substrate Details Istradefylline Relugolix Orgovyx Increased relugolix exposure Details Istradefylline Bedaquiline Sirturo Increased bedaquiline exposure Details Istradefylline Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Istradefylline Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Istradefylline Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Istradefylline Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Istradefylline Digoxin Cardoxin® Increased digoxin exposure Details Istradefylline Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Istradefylline Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Istradefylline Alfentanil Increased ALfentanil exposure and an increased risk of respiratory depression Details Istradefylline Apalutamide Erleada Decreased istradefylline exposure Details Istradefylline Artemether Increased artemether/lumefantrine exposure, an increased risk of QT prolongation, reduced CYP3A4 substrate exposure and reduced ef... Details Istradefylline Avacopan Tavneos Increased CYP3A4 substrate exposure Details Istradefylline Boceprevir Increased istradefylline exposure Details Istradefylline Carbamazepine Carbatrol Decreased istradefylline exposure Details Istradefylline Clarithromycin Biaxin Increased istradefylline exposure Details Istradefylline Cobicistat Tybost Increased istradefylline exposure Details Istradefylline Conivaptan Vaprisol Increased istradefylline exposure Details Istradefylline Cyclosporine Atopica Increased cycloSPORINE exposure Details Istradefylline Doxorubicin Hydrochloride Liposome Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Istradefylline Ensartinib Increased ensartinib exposure Details Istradefylline Enzalutamide Xtandi Decreased istradefylline exposure Details Istradefylline Erythromycin Erythrocin Stearate Increased CYP3A4 substrate exposure and an increased risk of CYP3A4-substrate-related adverse effects Details Istradefylline Fedratinib Inrebic Increased CYP3A4 substrate exposure Details Istradefylline Fexinidazole An increased CYP3A4 substrate exposure Details Istradefylline Fosphenytoin Cerebyx Decreased istradefylline exposure Details Istradefylline Haloperidol Increased haloperidol exposure and an increased risk of haloperidol-related adverse events, including QTc interval prolongation Details Istradefylline Idelalisib Zydelig Increased istradefylline exposure Details Istradefylline Indinavir Increased istradefylline exposure Details Istradefylline Itraconazole Sporanox Increased istradefylline exposure Details Istradefylline Ketoconazole Extina Increased istradefylline exposure Details Istradefylline Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Istradefylline Lemborexant Dayvigo Increased lemborexant exposure and an increased risk of lemborexant-related adverse reactions. Details Istradefylline Letermovir Prevymis Increased CYP3A substrate exposure Details Istradefylline Lomitapide Increased lomitapide exposure Details Istradefylline Loperamide Diamode An increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Istradefylline Lopinavir Increased istradefylline exposure Details