Alfalfa

Name: Alfalfa Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

9 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Azathioprine Cyclosporine Injection Cyclosporine Ophthalmic Mercaptopurine

4 Major 5 Minor

All (9) Major (4) Minor (5)

Major

Alfalfa Azathioprine Azasan Reduced immunosuppressive drug effectiveness and acute transplant rejection Details Alfalfa Cyclosporine Injection Atopica Reduced immunosuppressive drug effectiveness and acute transplant rejection Details Alfalfa Cyclosporine Ophthalmic Cequa Reduced immunosuppressive drug effectiveness and acute transplant rejection Details Alfalfa Mercaptopurine Purinethol® Reduced immunosuppressive drug effectiveness and acute transplant rejection Details

Minor

Alfalfa Defibrotide Injection Defitelio Reduced anticoagulant effectiveness Details Alfalfa Fondaparinux Arixtra Reduced anticoagulant effectiveness Details Alfalfa Fondaparinux Injection Arixtra Reduced anticoagulant effectiveness Details Alfalfa Heparin Reduced anticoagulant effectiveness Details Alfalfa Heparin Injection Lipo-Hepin® Reduced anticoagulant effectiveness Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.