Ganciclovir Injection

16 interactions 270 cited references
Also sold as: Cytovene® I.V.® Zirgan
About Ganciclovir Injection

Ganciclovir injection is used to treat cytomegalovirus (CMV) retinitis (eye infection that can cause blindness) in people whose immune system is not working normally, including those people who have acquired immunodeficiency syndrome (AIDS). It is also used to prevent CMV disease in transplant recipients at risk for CM… Read the full Ganciclovir Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Azathioprine Bupropion Clomipramine Emtricitabine Hydroxychloroquine Imipenem
13 Major 3 Moderate
All (16) Major (13) Moderate (3)

Major

Ganciclovir Injection Azathioprine Azasan An increased risk of hepatotoxicity Details Ganciclovir Injection Bupropion Aplenzin Increased risk of seizures Details Ganciclovir Injection Clomipramine Anafranil Increased risk of seizures Details Ganciclovir Injection Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Ganciclovir Injection Hydroxychloroquine Plaquenil An increased risk of seizures Details Ganciclovir Injection Imipenem CNS toxicity (seizures) Details Ganciclovir Injection Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Ganciclovir Injection Maribavir Livtencity Reduced ganciclovir or valGANciclovir exposure and reduced efficacy of ganciclovir or valGANciclovir Details Ganciclovir Injection Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Ganciclovir Injection Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Ganciclovir Injection Mycophenolate Mofetil Increased ganciclovir exposure and an increased risk of ganciclovir-related adverse reactions Details Ganciclovir Injection Tenofovir Alafenamide Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Ganciclovir Injection Tramadol ConZip An increased risk of seizure Details

Moderate

Ganciclovir Injection Didanosine Videx® An increased risk of didanosine toxicity (neuropathy, diarrhea, pancreatitis) Details Ganciclovir Injection Probenecid Increased risk for ganciclovir toxicity Details Ganciclovir Injection Tacrolimus Astagraf An increased risk of nephrotoxicity Details

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