Pentostatin

Name: Pentostatin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

4 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Cyclophosphamide Cyclophosphamide Injection Fludarabine Injection Nelarabine Injection

4 Major

All (4) Major (4)

Major

Pentostatin Cyclophosphamide Cytoxan® Cardiac toxicity Details Pentostatin Cyclophosphamide Injection Cytoxan® Injection Cardiac toxicity Details Pentostatin Fludarabine Injection Fludara® An increased risk of severe and fatal pulmonary toxicity Details Pentostatin Nelarabine Injection Arranon Reduced conversion of nelarabine to its active moiety, resulting in decreased nelarabine efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.