Leuprolide

63 interactions 4 explained in plain English 528 cited references

Also sold as: Eligard Fensolvi Lupron Lutrate Vabrinty

Read the full Leuprolide drug information page

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Hydroxychloroquine Ofloxacin Ophthalmic Oxaliplatin Injection Olodaterol Oral Inhalation Metronidazole Injection Asenapine Transdermal Patch

63 Major

All (63) Major (63)

Major

Leuprolide Amitriptyline Elavil Explained Increased risk of QT interval prolongation Details Leuprolide Sertraline Explained An increased risk of QT interval prolongation Details Leuprolide Buprenorphine Belbuca Explained An increased risk of QT interval prolongation Details Leuprolide Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Leuprolide Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Leuprolide Arsenic Trioxide Trisenox Increased risk of QT interval prolongation Details Leuprolide Aripiprazole Injection Abilify Increased risk of QT interval prolongation Details Leuprolide Arsenic Trioxide Injection Trisenox Increased risk of QT interval prolongation Details Leuprolide Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Leuprolide Azithromycin AzaSite Increased risk of QT interval prolongation Details Leuprolide Alfuzosin UroXatral Increased risk of QT interval prolongation Details Leuprolide Anagrelide Agrylin Increased risk of QT interval prolongation Details Leuprolide Bedaquiline Sirturo Increased risk of QT interval prolongation Details Leuprolide Chloroquine Aralen® Increased risk of QT interval prolongation Details Leuprolide Dasatinib Phyrago Increased risk of QT interval prolongation Details Leuprolide Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Leuprolide Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Leuprolide Disopyramide Norpace Increased risk of QT interval prolongation Details Leuprolide Dofetilide Tikosyn Increased risk of QT interval prolongation Details Leuprolide Dolasetron Anzemet Increased risk of QT interval prolongation Details Leuprolide Dolasetron Injection Anzemet Increased risk of QT interval prolongation Details Leuprolide Encorafenib Braftovi Increased risk of QT interval prolongation Details Leuprolide Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Leuprolide Eribulin Injection Halaven Increased risk of QT interval prolongation Details Leuprolide Famotidine Calmicid Increased risk of QT interval prolongation Details Leuprolide Famotidine Injection Calmicid Increased risk of QT interval prolongation Details Leuprolide Felbamate Felbatol Increased risk of QT interval prolongation Details Leuprolide Flecainide Tambocor® Increased risk of QT interval prolongation Details Leuprolide Foscarnet Injection Foscavir Increased risk of QT interval prolongation Details Leuprolide Fostemsavir Rukobia Increased risk of torsade de pointes Details Leuprolide Galantamine Razadyne Increased risk of QT interval prolongation Details Leuprolide Gatifloxacin Ophthalmic Zymar® Increased risk of QT interval prolongation Details Leuprolide Gemifloxacin Factive Increased risk of QT interval prolongation Details Leuprolide Glasdegib Daurismo Increased risk of QT interval prolongation Details Leuprolide Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Leuprolide Granisetron Transdermal Patch Sancuso Increased risk of QT interval prolongation Details Leuprolide Granisetron Injection Granisol Increased risk of QT interval prolongation Details Leuprolide Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Leuprolide Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Leuprolide Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.