Leuprolide

63 interactions 4 explained in plain English 528 cited references
Also sold as: Eligard Fensolvi Lupron Lutrate Vabrinty

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Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Hydroxychloroquine Ofloxacin Ophthalmic Oxaliplatin Injection Olodaterol Oral Inhalation Metronidazole Injection Asenapine Transdermal Patch
63 Major
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Major

Leuprolide Ivabradine Corlanor Increased risk of QT interval prolongation Details Leuprolide Ketoconazole Topical Extina® Foam Increased risk of QT interval prolongation Details Leuprolide Lefamulin Xenleta Increased risk of QT interval prolongation Details Leuprolide Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Leuprolide Levofloxacin Levaquin Increased risk of QT interval prolongation Details Leuprolide Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Leuprolide Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Leuprolide Mefloquine Lariam® Increased risk of QT interval prolongation Details Leuprolide Metronidazole Flagyl Increased risk of QT interval prolongation Details Leuprolide Metronidazole Injection Flagyl Increased risk of QT interval prolongation Details Leuprolide Metronidazole Topical MetroCream® Increased risk of QT interval prolongation Details Leuprolide Metronidazole Vaginal MetroGel® Vaginal Increased risk of QT interval prolongation Details Leuprolide Moxifloxacin Avelox Increased risk of QT interval prolongation Details Leuprolide Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Leuprolide Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Leuprolide Nafarelin Nasal Spray Synarel Increased risk of QT interval prolongation Details Leuprolide Octreotide Bynfezia Increased risk of QT interval prolongation Details Leuprolide Octreotide Injection Bynfezia Increased risk of QT interval prolongation Details Leuprolide Ofloxacin Floxin® Increased risk of QT interval prolongation Details Leuprolide Ofloxacin Ophthalmic Ocuflox Increased risk of QT interval prolongation Details Leuprolide Ofloxacin Otic Floxin® Otic Increased risk of QT interval prolongation Details Leuprolide Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Leuprolide Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

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