Pomalidomide

Name: Pomalidomide Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

3 interactions 1 explained in plain English

Also sold as: Pomalyst Pomalyst®

About Pomalidomide

Pomalidomide is used in combination with dexamethasone to treat multiple myeloma (a type of cancer of the bone marrow) that has not improved during or within 60 days of treatment with at least two other medications, including lenalidomide (Revlimid) and a proteasome inhibitor such as bortezomib (Velcade) or carfilzomib… Read the full Pomalidomide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abametapir Enasidenib

2 Major 1 Moderate

All (3) Major (2) Moderate (1)

Major

Pomalidomide Abametapir Explained Increased exposure of CYP1A2 substrates Details Pomalidomide Enasidenib Idhifa Increased CYP1A2 substrate exposure and an increased risk of CYP1A2 substrate-related adverse effects Details

Moderate

Pomalidomide Obeticholic Acid Ocaliva Increased exposure to CYP1A2 substrate Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.