Fermented Wheat Germ Extract - Pomalyst (Pomalidomide) Interaction

Interaction Details

Pomalidomide is classified as belonging to the following category: Immunosuppressants

Theoretically, fermented wheat germ extract might decrease the effects of immunosuppressants.
Animal research suggests that fermented wheat germ extract can stimulate immune function.

Interaction Rating

Likelihood of Occurrence

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

• Hidvegi M, Raso E, Tomoskozi Farkas R, Lapis K, Szende B. Effect of MSC on the immune response of mice. Immunopharmacology 1999;41(3):183-186.
• Sukkar SG, Rossi E. Oxidative stress and nutritional prevention in autoimmune rheumatic diseases. Autoimmun Rev 2004;3(3):199-206.
• Ehrenfeld M, Blank M, Shoenfeld Y, Hidvegi M. AVEMAR (a new benzoquinone-containing natural product) administration interferes with the Th2 response in experimental SLE and promotes amelioration of the disease. Lupus 2001;10(9):622-627.
• Gidali J, Hidvégi M, Fehér I, et al. The effect of Avemar treatment on the regeneration of leukocytes, thrombocytes and reticulocytes in sublethally irradiated or cyclophosphamide treated mice. First Congress of the Hungarian Society of Clinical Oncology,
• Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728.

Pomalidomide Overview

• Pomalidomide is used in combination with dexamethasone to treat multiple myeloma (a type of cancer of the bone marrow) that has not improved during or within 60 days of treatment with at least two other medications, including lenalidomide (Revlimid) and a proteasome inhibitor such as bortezomib (Velcade) or carfilzomib (Kyprolis). It is also used to treat Kaposi's sarcoma (a type of cancer that causes abnormal tissue to grow on different parts of the body) related to acquired immunodeficiency syndrome (AIDS) after unsuccessful treatment with other medications or in people with Kaposi's sarcoma who are do not have human immunodeficiency virus (HIV) infection. Pomalidomide is in a class of medications called immunomodulatory agents. It works by helping the bone marrow to produce normal blood cells and by killing abnormal cells in the bone marrow.

Fermented Wheat Germ Extract - More Interactions

Fermented Wheat Germ Extract interacts with 112 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.