Doxazosin

47 interactions 267 cited references
Also sold as: Cardura Cardura® Cardura® XL
About Doxazosin

Doxazosin is an alpha-blocker used to treat enlarged prostate symptoms and high blood pressure. Read the full Doxazosin drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Boceprevir Melphalan Injection Iloperidone Melphalan Milsaperidone Nifedipine
1 Contraindicated 11 Major 35 Moderate
All (47) Contraindicated (1) Major (11) Moderate (35)

Contraindicated

Doxazosin Boceprevir Increased doxazosin exposure Details

Major

Doxazosin Alfuzosin UroXatral Increased effects of alpha adrenergic blockade Details Doxazosin Iloperidone Fanapt Increased risk of symptomatic hypotension Details Doxazosin Melphalan Alkeran An increased risk of severe hypotension Details Doxazosin Milsaperidone An increased risk of symptomatic hypotension Details Doxazosin Nifedipine Adalat® Increased NIFEdipine exposure and an increased risk of hypotension Details Doxazosin Sildenafil Liqrev Potentiation of hypotensive effects Details Doxazosin Silodosin Rapaflo Increased effects of alpha adrenergic blockade Details Doxazosin Tadalafil Adcirca Increased risk of hypotension Details Doxazosin Tamsulosin Flomax Increased effects of alpha adrenergic blockade Details Doxazosin Vardenafil Levitra Potentiation of hypotensive effects Details Doxazosin Melphalan Injection Alkeran An increased risk of severe hypotension Details

Moderate

Doxazosin Asenapine Transdermal Patch Secuado An increased risk of hypotension Details Doxazosin Atenolol Tenormin An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Acebutolol Sectral® An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Avanafil Stendra Increased risk of hypotension Details Doxazosin Betaxolol Betoptic S An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Betaxolol Ophthalmic Betoptic® An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Bisoprolol Zebeta® An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Alprenolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Asenapine Saphris An increased risk of hypotension Details Doxazosin Bevantolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Bucindolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Carteolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Carvedilol Coreg An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Celiprolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Dilevalol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Esmolol Brevibloc An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Labetalol Normodyne® An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Levobunolol Betagan An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Ma Huang Reduced effectiveness of alpha-1 adrenergic blockers Details Doxazosin Mepindolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Metipranolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Metoprolol Kapspargo An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Midodrine Orvaten® Decreased midodrine effectiveness Details Doxazosin Nadolol Corgard An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Nebivolol Bystolic An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Oxprenolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Penbutolol Levatol® An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Pindolol Visken® An exaggerated hypotensive response to the first dose of the alpha blocker Details

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