Doxazosin

Name: Doxazosin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

47 interactions 267 cited references

Also sold as: Cardura Cardura® Cardura® XL

About Doxazosin

Doxazosin is an alpha-blocker used to treat enlarged prostate symptoms and high blood pressure. Read the full Doxazosin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Boceprevir Melphalan Injection Iloperidone Melphalan Milsaperidone Nifedipine

1 Contraindicated 11 Major 35 Moderate

All (47) Contraindicated (1) Major (11) Moderate (35)

Moderate

Doxazosin Propranolol Hemangeol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Sotalol Betapace An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Talinolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Tertatolol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Timolol Betimol An exaggerated hypotensive response to the first dose of the alpha blocker Details Doxazosin Yohimbine Reduced alpha-1 adrenergic blocker effectiveness Details Doxazosin Levobunolol Ophthalmic AKBeta® An exaggerated hypotensive response to the first dose of the alpha blocker Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.