Doxazosin

Name: Doxazosin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

47 interactions 267 cited references

Also sold as: Cardura Cardura® Cardura® XL

About Doxazosin

Doxazosin is an alpha-blocker used to treat enlarged prostate symptoms and high blood pressure. Read the full Doxazosin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Boceprevir Melphalan Injection Iloperidone Melphalan Milsaperidone Nifedipine

1 Contraindicated 11 Major 35 Moderate

All (47) Contraindicated (1) Major (11) Moderate (35)

Major

Doxazosin Alfuzosin UroXatral Increased effects of alpha adrenergic blockade Details Doxazosin Iloperidone Fanapt Increased risk of symptomatic hypotension Details Doxazosin Melphalan Alkeran An increased risk of severe hypotension Details Doxazosin Milsaperidone An increased risk of symptomatic hypotension Details Doxazosin Nifedipine Adalat® Increased NIFEdipine exposure and an increased risk of hypotension Details Doxazosin Sildenafil Liqrev Potentiation of hypotensive effects Details Doxazosin Silodosin Rapaflo Increased effects of alpha adrenergic blockade Details Doxazosin Tadalafil Adcirca Increased risk of hypotension Details Doxazosin Tamsulosin Flomax Increased effects of alpha adrenergic blockade Details Doxazosin Vardenafil Levitra Potentiation of hypotensive effects Details Doxazosin Melphalan Injection Alkeran An increased risk of severe hypotension Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.