Saquinavir

176 interactions 13 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Simvastatin Eribulin Injection Levofloxacin Injection Goserelin Implant Arsenic Trioxide Felbamate

74 Contraindicated 83 Major 19 Moderate

All (176) Contraindicated (74) Major (83) Moderate (19)

Contraindicated

Saquinavir Amitriptyline Elavil Explained An increased risk of QT interval prolongation Details Saquinavir Sertraline Explained An increased risk of QT interval prolongation Details Saquinavir Buprenorphine Belbuca Explained An increased risk of QT interval prolongation Details Saquinavir Relugolix Orgovyx Explained An increased risk of QT interval prolongation Details Saquinavir Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of fatal toxicity Details Saquinavir Simvastatin Flolipid Explained Increased risk of myopathy or rhabdomyolysis Details Saquinavir Amisulpride Injection Barhemsys An increased risk of QT interval prolongation Details Saquinavir Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Saquinavir Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Saquinavir Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation Details Saquinavir Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation Details Saquinavir Azithromycin AzaSite An increased risk of QT interval prolongation Details Saquinavir Alfuzosin UroXatral Increased alfuzosin plasma concentrations Details Saquinavir Anagrelide Agrylin An increased risk of QT interval prolongation Details Saquinavir Bedaquiline Sirturo Increased bedaquiline exposure and an increased risk of QT interval prolongation Details Saquinavir Chloroquine Aralen® An increased risk of QT interval prolongation Details Saquinavir Dasatinib Phyrago An increased risk of QT interval prolongation Details Saquinavir Degarelix Injection Firmagon An increased risk of QT interval prolongation Details Saquinavir Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Saquinavir Dihydroergotamine Injection DHE-45® Injection Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Saquinavir Dihydroergotamine Nasal Spray Migranal Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Saquinavir Dofetilide Tikosyn Increased dofetilide exposure and increased risk of QT interval prolongation Details Saquinavir Dolasetron Anzemet An increased risk of QT interval prolongation Details Saquinavir Dolasetron Injection Anzemet An increased risk of QT interval prolongation Details Saquinavir Encorafenib Braftovi An increased risk of QT interval prolongation, increased encorafenib exposure and an increased risk of encorafenib-related adverse... Details Saquinavir Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Saquinavir Eribulin Injection Halaven An increased risk of QT interval prolongation Details Saquinavir Famotidine Calmicid An increased risk of QT interval prolongation Details Saquinavir Famotidine Injection Calmicid An increased risk of QT interval prolongation Details Saquinavir Felbamate Felbatol An increased risk of QT interval prolongation Details Saquinavir Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Saquinavir Flecainide Tambocor® Increased flecainide plasma concentrations and increased risk for serious cardiac arrhythmia Details Saquinavir Foscarnet Injection Foscavir An increased risk of QT interval prolongation Details Saquinavir Fostemsavir Rukobia An increased risk of QT interval prolongation Details Saquinavir Galantamine Razadyne An increased risk of QT interval prolongation Details Saquinavir Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation Details Saquinavir Gemifloxacin Factive An increased risk of QT interval prolongation Details Saquinavir Glasdegib Daurismo An increased risk of QT interval prolongation Details Saquinavir Goserelin Implant Zoladex An increased risk of QT interval prolongation Details Saquinavir Granisetron Transdermal Patch Sancuso An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.