Lisinopril
196 interactions 135 explained in plain English 638 cited referencesLisinopril is an ACE inhibitor used to treat high blood pressure, heart failure, and improve survival after a heart attack. Read the full Lisinopril drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Contraindicated
Lisinopril Aliskiren Tekturna An increased risk of hyperkalemia, renal impairment, and hypotension Details Lisinopril Sacubitril Explained Increased risk of angioedema Details Lisinopril Valsartan Diovan Explained Increased risk of angioedema and an increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal fun... DetailsMajor
Lisinopril Alteplase, Recombinant Activase Explained An increased risk of orolingual angioedema Details Lisinopril Amiloride Explained Increased risk of hyperkalemia Details Lisinopril Aspirin Acuprin® Explained Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Lisinopril Azathioprine Azasan Explained Myelosuppression Details Lisinopril Azilsartan Edarbi Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Lisinopril Azilsartan Medoxomil Edarbi Explained Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Lisinopril Candesartan Atacand Explained Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Lisinopril Canrenoate Explained Increased risk of hyperkalemia Details Lisinopril Cyclosporine Atopica Explained Acute renal dysfunction and an increased risk of hyperkalemia Details Lisinopril Digoxin Cardoxin® An increased digoxin exposure Details Lisinopril Eplerenone Inspra Explained Increased risk of hyperkalemia Details Lisinopril Eprosartan Teveten® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Lisinopril Everolimus Afinitor Increased risk of angioedema Details Lisinopril Furosemide Disal Explained An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Lisinopril Insulin Icodec-Abae Awiqli Explained An increased risk of hypoglycemia Details Lisinopril Irbesartan Avapro Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Lisinopril Lithium Explained Increased risk of lithium toxicity Details Lisinopril Losartan Arbli Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Lisinopril Melphalan Alkeran An increased risk of severe hypotension Details Lisinopril Mercaptopurine Purinethol® Myelosuppression Details Lisinopril Olmesartan Benicar Explained Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Lisinopril Potassium Glu-K® Explained Hyperkalemia Details Lisinopril Potassium Citrate Urocit-K Explained Increased risk of hyperkalemia Details Lisinopril Potassium Phosphate K-Phos Explained Increased risk of severe and potentially fatal hyperkalemia Details Lisinopril Pregabalin Bonqat Explained Increased risk of angioedema Details Lisinopril Sirolimus Felycin Explained Increased risk of angioedema Details Lisinopril Spironolactone Aldactone Explained Increased risk of hyperkalemia Details Lisinopril Tacrolimus Astagraf Explained An increased risk of hyperkalemia Details Lisinopril Telmisartan Micardis Explained Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Lisinopril Temsirolimus Torisel Explained Increased risk of angioedema Details Lisinopril Triamterene Dyrenium Explained Increased risk of hyperkalemia Details Lisinopril Trimethoprim Primsol Explained Increased risk of hyperkalemia Details Lisinopril Aspirin Rectal Aspirin Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Lisinopril Cyclosporine Injection Atopica Acute renal dysfunction and an increased risk of hyperkalemia Details Lisinopril Cyclosporine Ophthalmic Cequa Acute renal dysfunction and an increased risk of hyperkalemia Details Lisinopril Furosemide Injection Disal An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Lisinopril Lithium Carbonate Lithobid Increased risk of lithium toxicity DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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