Rilzabrutinib

Major

Rilzabrutinib Omeprazole Gastrobim Explained Reduced rilzabrutinib exposure, reduced efficacy of rilzabrutinib, an increased omeprazole exposure and an increased risk of omepr... Details Rilzabrutinib Dexamethasone Injection Decadron Reduced rilzabrutinib exposure, reduced efficacy of rilzabrutinib, increased CYP3A substrate exposure and an increased risk of CYP... Details Rilzabrutinib Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced rilzabrutinib exposure, reduced efficacy of rilzabrutinib, increased CYP3A substrate exposure and an increased risk of CYP... Details Rilzabrutinib Dexlansoprazole Dexilant Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details Rilzabrutinib Encorafenib Braftovi Reduced rilzabrutinib exposure, reduced efficacy of rilzabrutinib, increased CYP3A substrate exposure and an increased risk of CYP... Details Rilzabrutinib Esomeprazole Nexium Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details Rilzabrutinib Esomeprazole Injection Nexium Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details Rilzabrutinib Famotidine Calmicid Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details Rilzabrutinib Famotidine Injection Calmicid Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details Rilzabrutinib Ketoconazole Topical Extina® Foam Increased rilzabrutinib exposure, an increased risk of rilzabrutinib-related adverse reactions, an increased CYP3A substrate expos... Details Rilzabrutinib Lansoprazole Prevacid Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details Rilzabrutinib Lefamulin Xenleta Increased rilzabrutinib exposure, an increased risk of rilzabrutinib-related adverse reactions, increased CYP3A substrate exposure... Details Rilzabrutinib Lenacapavir Injection Sunlenca Increased rilzabrutinib exposure, an increased risk of rilzabrutinib-related adverse reactions, increased CYP3A substrate exposure... Details Rilzabrutinib Lenacapavir Oral Sunlenca Increased rilzabrutinib exposure, an increased risk of rilzabrutinib-related adverse reactions, increased CYP3A substrate exposure... Details Rilzabrutinib Letermovir Injection Prevymis Increased rilzabrutinib exposure and an increased risk of rilzabrutinib-related adverse reactions Details Rilzabrutinib Mitapivat Aqvesme Reduced rilzabrutinib exposure, reduced efficacy of rilzabrutinib, increased CYP3A substrate exposure and an increased risk of CYP... Details Rilzabrutinib Nafcillin Injection Unipen® Injection Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details Rilzabrutinib Nizatidine Axid® Reduced rilzabrutinib exposure and reduced efficacy of rilzabrutinib Details

Moderate

Rilzabrutinib Acetaminophen And Codeine Capital® & Codeine Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Clindamycin ANTIROBE Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Sertraline Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Buprenorphine Belbuca Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Colchicine Colcrys Explained Increased P-gp substrate with NTI exposure and an increased risk of P-gp substrate with NTI-related adverse reactions Details Rilzabrutinib Simvastatin Flolipid Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Abemaciclib Verzenio Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Acalabrutinib Calquence Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Alpelisib Piqray Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Apixaban Eliquis Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Aripiprazole Injection Abilify Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Asciminib Scemblix Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Atogepant Qulipta Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Avapritinib Ayvakit Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Avatrombopag Doptelet Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Belumosudil Rezurock Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Atorvastatin Atorvaliq Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Cariprazine Vraylar Explained Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Abiraterone Abirtega Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Alfuzosin UroXatral Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Amlodipine Amvaz® Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Rilzabrutinib Avanafil Stendra Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details