Dasabuvir

21 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Lovastatin Levonorgestrel Intrauterine System Levonorgestrel Gemfibrozil Nevirapine Ketoconazole Topical
5 Contraindicated 14 Major 2 Moderate
All (21) Contraindicated (5) Major (14) Moderate (2)

Contraindicated

Dasabuvir Gemfibrozil Lopid Increased dasabuvir exposure and an increased risk of QT interval prolongation Details Dasabuvir Levonorgestrel After banger An increased risk of ALT elevation Details Dasabuvir Levonorgestrel Intrauterine System Kyleena An increased risk of ALT elevation Details Dasabuvir Lovastatin Altocor® Increased lovastatin exposure and an increased risk of lovastatin-related adverse effects, such as risk of myopathy and rhabdomyol... Details Dasabuvir Nevirapine Viramune Decreased dasabuvir exposure and reduced effect Details

Major

Dasabuvir Omeprazole Gastrobim Explained Increased dasabuvir concentration; decreased omeprazole concentration Details Dasabuvir Alpelisib Piqray Increased alpelisib exposure and an increased risk of alpelisib-related adverse effects and toxicity Details Dasabuvir Cyclosporine Injection Atopica Increased cycloSPORINE concentrations; increased dasabuvir concentrations Details Dasabuvir Cyclosporine Ophthalmic Cequa Increased cycloSPORINE concentrations; increased dasabuvir concentrations Details Dasabuvir Disopyramide Norpace Increased plasma concentration of antiarrhythmic agent Details Dasabuvir Dolutegravir Juluca® (as a combination product containing dolutegravir, rilpivirine) Increased dasabuvir and dolutegravir plasma concentrations Details Dasabuvir Doxorubicin Adriamycin Increased dasabuvir and doxorubicin plasma concentrations Details Dasabuvir Flecainide Tambocor® Increased plasma concentration of antiarrhythmic agent Details Dasabuvir Furosemide Injection Disal Increased furosemide exposure Details Dasabuvir Ketoconazole Topical Extina® Foam Increased dasabuvir concentrations; increased ketoconazole concentrations Details Dasabuvir Leflunomide Arava Increased exposure of CYP2C8 substrate Details Dasabuvir Metformin Fortamet® Increased risk of lactic acidosis Details Dasabuvir Mexiletine Mexitil® Increased plasma concentration of antiarrhythmic agent Details Dasabuvir Montelukast Singulair Increased dasabuvir concentration Details

Moderate

Dasabuvir Finerenone Kerendia Increased CYP2C8 substrate exposure and an increased risk of CYP2C8 substrate-related adverse effects Details Dasabuvir Mitapivat Aqvesme Reduced CYP2C8 substrate exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.