Dasabuvir

21 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Lovastatin Levonorgestrel Intrauterine System Levonorgestrel Gemfibrozil Nevirapine Ketoconazole Topical
5 Contraindicated 14 Major 2 Moderate
All (21) Contraindicated (5) Major (14) Moderate (2)

Major

Dasabuvir Omeprazole Gastrobim Explained Increased dasabuvir concentration; decreased omeprazole concentration Details Dasabuvir Alpelisib Piqray Increased alpelisib exposure and an increased risk of alpelisib-related adverse effects and toxicity Details Dasabuvir Cyclosporine Injection Atopica Increased cycloSPORINE concentrations; increased dasabuvir concentrations Details Dasabuvir Cyclosporine Ophthalmic Cequa Increased cycloSPORINE concentrations; increased dasabuvir concentrations Details Dasabuvir Disopyramide Norpace Increased plasma concentration of antiarrhythmic agent Details Dasabuvir Dolutegravir Juluca® (as a combination product containing dolutegravir, rilpivirine) Increased dasabuvir and dolutegravir plasma concentrations Details Dasabuvir Doxorubicin Adriamycin Increased dasabuvir and doxorubicin plasma concentrations Details Dasabuvir Flecainide Tambocor® Increased plasma concentration of antiarrhythmic agent Details Dasabuvir Furosemide Injection Disal Increased furosemide exposure Details Dasabuvir Ketoconazole Topical Extina® Foam Increased dasabuvir concentrations; increased ketoconazole concentrations Details Dasabuvir Leflunomide Arava Increased exposure of CYP2C8 substrate Details Dasabuvir Metformin Fortamet® Increased risk of lactic acidosis Details Dasabuvir Mexiletine Mexitil® Increased plasma concentration of antiarrhythmic agent Details Dasabuvir Montelukast Singulair Increased dasabuvir concentration Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.