Nimesulide Beta Cyclodextrin

91 interactions 5 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Nasal Spray Ketorolac Injection Ketorolac Ophthalmic Ketorolac Pemetrexed Injection Epoprostenol

4 Contraindicated 59 Major 28 Moderate

All (91) Contraindicated (4) Major (59) Moderate (28)

Contraindicated

Nimesulide Beta Cyclodextrin Ketorolac Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Nimesulide Beta Cyclodextrin Ketorolac Injection Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Nimesulide Beta Cyclodextrin Ketorolac Nasal Spray Sprix Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Nimesulide Beta Cyclodextrin Ketorolac Ophthalmic Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details

Major

Nimesulide Beta Cyclodextrin Amitriptyline Elavil Explained An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Sertraline Explained An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Apixaban Eliquis Explained An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Aspirin Acuprin® An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Nimesulide Beta Cyclodextrin Aspirin Rectal Aspirin An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Nimesulide Beta Cyclodextrin Betrixaban Bevyxxa® An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Anagrelide Agrylin An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Bromfenac Ophthalmic Bromday® Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Nimesulide Beta Cyclodextrin Budesonide Nasal Spray Rhinocort Increased risk of gastrointestinal ulcer or bleeding Details Nimesulide Beta Cyclodextrin Budesonide Oral Inhalation Pulmicort Increased risk of gastrointestinal ulcer or bleeding Details Nimesulide Beta Cyclodextrin Clopidogrel Plavix An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Cyclosporine Injection Atopica An increased risk of cycloSPORINE nephrotoxicity Details Nimesulide Beta Cyclodextrin Cyclosporine Ophthalmic Cequa An increased risk of cycloSPORINE nephrotoxicity Details Nimesulide Beta Cyclodextrin Dabigatran Pradaxa® An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Dabigatran Etexilate An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Dalteparin Injection Fragmin An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Nimesulide Beta Cyclodextrin Dexamethasone Injection Decadron Increased risk of gastrointestinal ulcer or bleeding Details Nimesulide Beta Cyclodextrin Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of gastrointestinal ulcer or bleeding Details Nimesulide Beta Cyclodextrin Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Diclofenac Transdermal Patch Flector Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Digoxin Cardoxin® Increased digoxin exposure and prolonged half-life of digoxin Details Nimesulide Beta Cyclodextrin Dipyridamole Permole® An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Edoxaban Savaysa An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Nimesulide Beta Cyclodextrin Enoxaparin Lovenox An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Enoxaparin Injection Lovenox An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Epoprostenol Flolan An increased risk of bleeding Details Nimesulide Beta Cyclodextrin Etodolac Lodine Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Fenoprofen Fenopron Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Flurbiprofen Ansaid Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Flurbiprofen Ophthalmic Ocufen Increased risk of bleeding Details Nimesulide Beta Cyclodextrin Fondaparinux Arixtra An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.