Pegaspargase Injection

15 interactions 57 cited references
Also sold as: Oncaspar Oncaspar®
About Pegaspargase Injection

Pegaspargase is used with other chemotherapy drugs to treat a certain type of acute lymphocytic leukemia (ALL; a type of cancer of the white blood cells). Pegaspargase is also used with other chemotherapy drugs to treat a certain type of ALL in people who have had some types of allergic reactions to medications similar… Read the full Pegaspargase Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Measles Virus Vaccine, Live Varicella Virus Vaccine, Live
9 Contraindicated 6 Major
All (15) Contraindicated (9) Major (6)

Contraindicated

Pegaspargase Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Pegaspargase Injection Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Pegaspargase Injection Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Pegaspargase Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Pegaspargase Injection Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pegaspargase Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.