Nivolumab Injection

21 interactions 532 cited references
Also sold as: Opdivo Opdivo®
About Nivolumab Injection

Nivolumab injection is used alone or in combination with ipilimumab (Yervoy) to treat certain types of melanoma (a type of skin cancer) in adults and children 12 years of age or older that has spread to other parts of the body or cannot be removed by surgery. It is also used alone to prevent melanoma from returning aft… Read the full Nivolumab Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Yellow Fever Vaccine Smallpox Monkeypox Vaccine Bacillus Of Calmette And Guerin Vaccine, Live Rubella Virus Vaccine, Live Dengue Tetravalent Vaccine, Live Mumps Virus Vaccine, Live
9 Contraindicated 12 Major
All (21) Contraindicated (9) Major (12)

Contraindicated

Nivolumab Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Nivolumab Injection Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Nivolumab Injection Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Nivolumab Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Nivolumab Injection Dexlansoprazole Dexilant Reduced efficacy of nivolumab Details Nivolumab Injection Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Esomeprazole Nexium Reduced efficacy of nivolumab Details Nivolumab Injection Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Nivolumab Injection Lansoprazole Prevacid Reduced efficacy of nivolumab Details Nivolumab Injection Omeprazole Gastrobim Reduced efficacy of nivolumab Details Nivolumab Injection Pantoprazole Protonix Reduced efficacy of nivolumab Details Nivolumab Injection Rabeprazole Aciphex Reduced efficacy of nivolumab Details Nivolumab Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.