Furosemide

105 interactions 5 explained in plain English
Also sold as: Disal Furoscix Lasix Salix - substance
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Furosemide Acetaminophen And Codeine Capital® & Codeine Explained Reduced diuretic efficacy Details Furosemide Albuterol Oral Inhalation Accuneb® Explained An increased risk of ECG changes or hypokalemia Details Furosemide Lisinopril Prinivil Explained An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Furosemide Buprenorphine Belbuca Explained Reduced efficacy of diuretics Details Furosemide Acarbose Prandase® Explained An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Amikacin Injection Amikin® Increased amikacin exposure and an increased risk of ototoxicity and/or nephrotoxicity Details Furosemide Amikacin Oral Inhalation Arikayce Increased amikacin exposure and an increased risk of ototoxicity and/or nephrotoxicity Details Furosemide Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Furosemide Arsenic Trioxide Injection Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Furosemide Aspirin Acuprin® An increased risk of salicylate toxicity and reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Aspirin Rectal Aspirin An increased risk of salicylate toxicity and reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Benazepril Lotensin An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Furosemide Alogliptin Nesina An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Azilsartan Edarbi Severe hypotension and deterioration in renal function, including renal failure Details Furosemide Bromfenac Ophthalmic Bromday® Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Canagliflozin Invokana An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Captopril Capoten® An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Furosemide Cefaclor Ceclor® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefadroxil Duricef® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefazolin Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefazolin Injection Ancef® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefdinir Omnicef® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefepime Injection Maxipime® An increased risk of nephrotoxicity Details Furosemide Cefixime Suprax Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefotetan Injection Cefotan Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefoxitin Injection Mefoxin® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefprozil Cefzil® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Ceftaroline Injection Teflaro® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Ceftazidime Injection Fortaz An increased risk of nephrotoxicity Details Furosemide Ceftriaxone Injection Rocephin® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cefuroxime Injection Kefurox® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cephalexin Keflet® Tablets Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Cisplatin Injection Platinol-AQ® An increased ototoxicity and an increased risk of nephrotoxicity Details Furosemide Dapagliflozin Farxiga An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Diclofenac Ophthalmic Voltaren® Eye Drops Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Diclofenac Transdermal Patch Flector Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Dulaglutide Injection Trulicity An increased risk of hyperglycemia and an increased insulin requirement Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.