Abatacept

51 interactions 44 explained in plain English 71 cited references
Also sold as: Orencia
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 16, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Adalimumab Injection Brodalumab Injection Golimumab Injection Adalimumab Alefacept Anifrolumab-Fnia
33 Major 18 Moderate
All (51) Major (33) Moderate (18)

Moderate

Abatacept Poliovirus Vaccine, Live Explained Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Rotavirus Vaccine, Live Explained Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Rubella Virus Vaccine, Live Explained Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Sars-Cov-2 (Covid-19) Vaccine, Adenovirus 26 Vector (Janssen) Explained Decreased immune response to COVID-19 vaccine Details Abatacept Sars-Cov-2 (Covid-19) Vaccine, Mrna (Moderna) Explained Decreased immune response to COVID-19 vaccine Details Abatacept Sars-Cov-2 (Covid-19) Vaccine, Mrna (Pfizer) Explained Decreased immune response to COVID-19 vaccine Details Abatacept Smallpox Monkeypox Vaccine Explained Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Typhoid Vaccine, Live Vivotif Explained Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Varicella Virus Vaccine, Live Explained Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Yellow Fever Vaccine Stamaril Explained Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details Abatacept Zoster Vaccine, Live Explained Secondary transmission of infection by the live vaccine; reduced effectiveness of immunization Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.