Aripiprazole Injection

347 interactions 801 cited references

Also sold as: Abilify Abilify Maintena® Abilify® Aristad Initio® Aristada® Opipza

About Aripiprazole Injection

Aripiprazole extended-release injection (Abilify Maintena, Aristada, Aristada Initio) is used alone or in combination with other aripiprazole preparations to treat schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Aripiprazole ext… Read the full Aripiprazole Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mavorixafor Mesoridazine Metoclopramide Pimozide Piperaquine Posaconazole

20 Contraindicated 316 Major 11 Moderate

All (347) Contraindicated (20) Major (316) Moderate (11)

Major

Aripiprazole Injection Ofloxacin Floxin® An increased risk of QT interval prolongation Details Aripiprazole Injection Olanzapine An increased risk of QT interval prolongation and an increased risk of CNS depression Details Aripiprazole Injection Oliceridine Olinvyk An increased risk of hypotension, respiratory depression, profound sedation, coma, and death Details Aripiprazole Injection Olodaterol Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Aripiprazole Injection Omaveloxolone Skyclarys Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Aripiprazole Injection Ondansetron An increased risk of QT interval prolongation Details Aripiprazole Injection Osilodrostat Isturisa Increased risk of QT interval prolongation Details Aripiprazole Injection Osimertinib Tagrisso Increased risk of QT interval prolongation Details Aripiprazole Injection Oxaliplatin Increased risk of QT-interval prolongation Details Aripiprazole Injection Oxazepam An increased risk of sedation and orthostatic hypotension Details Aripiprazole Injection Oxycodone Oxaydo Increased risk of respiratory and CNS depression Details Aripiprazole Injection Oxymorphone Increased risk of respiratory and CNS depression Details Aripiprazole Injection Ozanimod Additive effects on heart rate Details Aripiprazole Injection Pacritinib Vonjo® An increased risk of QT interval prolongation Details Aripiprazole Injection Paliperidone Erzofri An increased risk of CNS depression, an increased risk of QT interval prolongation and torsade de pointes Details Aripiprazole Injection Panobinostat Farydak Increased risk of QT interval prolongation Details Aripiprazole Injection Papaverine Pavacot® An increased risk of QT interval prolongation Details Aripiprazole Injection Paritaprevir Increased ARIPiprazole exposure Details Aripiprazole Injection Paroxetine Paxil Increased ARIPiprazole exposure and an increased risk of QT interval prolongation Details Aripiprazole Injection Pasireotide Signifor An increased risk of QT interval prolongation Details Aripiprazole Injection Pazopanib Votrient An increased risk of QT interval prolongation Details Aripiprazole Injection Pentamidine NebuPent An increased risk of QT interval prolongation Details Aripiprazole Injection Periciazine Risk of enhanced CNS depression Details Aripiprazole Injection Perphenazine An increased risk of QT interval prolongation Details Aripiprazole Injection Phenobarbital Fidoquel An increased risk of QT interval prolongation, an increased risk of CNS depression, reduced ARIPiprazole exposure and reduced effi... Details Aripiprazole Injection Phenytoin Dilantin Reduced ARIPiprazole exposure Details Aripiprazole Injection Pimavanserin Nuplazid An increased risk of QT interval prolongation Details Aripiprazole Injection Pinazepam An increased risk of sedation and orthostatic hypotension Details Aripiprazole Injection Pipamperone An increased risk of QT interval prolongation Details Aripiprazole Injection Pitolisant Wakix Increased risk of QT interval prolongation Details Aripiprazole Injection Ponesimod Ponvory An increased risk of QT interval prolongation Details Aripiprazole Injection Potassium Oxybate Xywav An increased risk of CNS depression and clinically significant respiratory depression, obtundation, hypotension, profound sedation... Details Aripiprazole Injection Prazepam An increased risk of sedation and orthostatic hypotension Details Aripiprazole Injection Pregabalin Bonqat An increased risk of respiratory depression Details Aripiprazole Injection Primidone Mysoline An increased risk of QT interval prolongation, an increased risk of CNS depression, reduced ARIPiprazole exposure and reduced effi... Details Aripiprazole Injection Probucol An increased risk of QT interval prolongation Details Aripiprazole Injection Procainamide Procan® An increased risk of QT interval prolongation Details Aripiprazole Injection Prochlorperazine An increased risk of QT interval prolongation Details Aripiprazole Injection Promethazine Phenadoz Increased risk of respiratory, profound sedation, hypotension, coma, death and an increased risk of QT prolongation Details Aripiprazole Injection Propafenone Rythmol An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.