Artemether
180 interactions 12 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Ketoconazole Topical
Famotidine
Olaparib
Dasatinib
Oxaliplatin Injection
Galantamine
Moderate
Artemether Deuruxolitinib Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Diazepam Nasal Spray Valtoco Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Diazepam Rectal Diastat Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Dihydroergotamine Injection DHE-45® Injection Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Dihydroergotamine Nasal Spray Migranal Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Docetaxel Beizray Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Docetaxel Injection Beizray Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Dolutegravir Juluca® (as a combination product containing dolutegravir, rilpivirine) Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Doravirine Pifeltro Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Elacestrant Orserdu Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Enasidenib Idhifa Reduced artemether/lumefantrine exposure, reduced efficacy of artemether/lumefantrine and loss of antimalarial efficacy Details Artemether Eravacycline Injection Xerava Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Esketamine Nasal Spray Spravato Increased artemether/lumefantrine exposure and an increased risk of potentiated QT prolongation Details Artemether Esomeprazole Nexium Increased artemether/lumefantrine exposure and an increased risk of potentiated QT prolongation Details Artemether Esomeprazole Injection Nexium Increased artemether/lumefantrine exposure and an increased risk of potentiated QT prolongation Details Artemether Estradiol Delestrogen Reduced hormonal contraceptive exposure and an increased artemether/lumefantrine exposure Details Artemether Estradiol Topical Divigel Reduced hormonal contraceptive exposure and an increased artemether/lumefantrine exposure Details Artemether Estradiol Transdermal Patch Alora® Reduced hormonal contraceptive exposure and an increased artemether/lumefantrine exposure Details Artemether Felodipine Plendil® Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Fentanyl Transdermal Patch Duragesic® Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Finerenone Kerendia Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Fostemsavir Rukobia Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Futibatinib Lytgobi Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Gilteritinib Xospata Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Guanfacine Intuniv Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Hydrocortisone Ala-Cort Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Hydrocortisone Injection A-Hydrocort® Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Ibrutinib Imbruvica Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Ifosfamide Injection Ifex Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Infigratinib Truseltiq Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Irinotecan Camptosar Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Irinotecan Injection Camptosar Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Irinotecan Lipid Complex Injection Onivyde® Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Ixazomib Ninlaro Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Lanthanum Fosrenol® Reduced bioavailability of antimalarials Details Artemether Leniolisib Joenja Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Levonorgestrel After banger Reduced hormonal contraceptive exposure and an increased artemether/lumefantrine exposure Details Artemether Levonorgestrel Intrauterine System Kyleena Reduced hormonal contraceptive exposure and an increased artemether/lumefantrine exposure Details Artemether Loratadine Agistam® Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Lovastatin Altocor® Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate 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