Artemether

180 interactions 12 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketoconazole Topical Famotidine Olaparib Dasatinib Oxaliplatin Injection Galantamine
1 Contraindicated 83 Major 96 Moderate
All (180) Contraindicated (1) Major (83) Moderate (96)

Moderate

Artemether Lurbinectedin Injection Zepzelca Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Macitentan Opsumit Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Maraviroc Selzentry Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Medroxyprogesterone Amen® Reduced hormonal contraceptive exposure and an increased artemether/lumefantrine exposure Details Artemether Medroxyprogesterone Injection Depo-Provera Reduced hormonal contraceptive exposure and an increased artemether/lumefantrine exposure Details Artemether Midazolam Nasal Spray Nayzilam Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Midazolam Injection Nayzilam Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Midostaurin Rydapt Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Nafcillin Injection Unipen® Injection Reduced artemether/lumefantrine exposure, reduced efficacy of artemether/lumefantrine and loss of antimalarial efficacy Details Artemether Naldemedine Symproic Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Naloxegol Movantik Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Nateglinide Starlix® Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Neratinib Nerlynx Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Nifedipine Adalat® Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Nintedanib Ofev Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Artemether Nisoldipine Sular Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details

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