Betrixaban

207 interactions 1 explained in plain English 188 cited references

Also sold as: Bevyxxa®

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Venlafaxine Omadacycline Injection Verapamil Venetoclax Vorapaxar Vimseltinib

202 Major 5 Moderate

All (207) Major (202) Moderate (5)

Major

Betrixaban Sertraline An increased risk of bleeding Details Betrixaban Apixaban Eliquis Explained Increased risk of bleeding Details Betrixaban Aspirin Acuprin® Increased risk of bleeding Details Betrixaban Aspirin Rectal Aspirin Increased risk of bleeding Details Betrixaban Abciximab Increased risk of bleeding Details Betrixaban Aceclofenac An increased risk of bleeding Details Betrixaban Acemetacin An increased risk of bleeding Details Betrixaban Acenocoumarol Increased risk of bleeding Details Betrixaban Alteplase, Recombinant Activase Increased risk of bleeding Details Betrixaban Amiodarone Nexterone Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Amtolmetin Guacil An increased risk of bleeding Details Betrixaban Anagrelide Agrylin Increased risk of bleeding Details Betrixaban Anistreplase Increased risk of bleeding Details Betrixaban Apalutamide Erleada Decreased betrixaban exposure Details Betrixaban Ardeparin Increased risk of bleeding Details Betrixaban Argatroban Increased risk of bleeding Details Betrixaban Atazanavir Reyataz Increased betrixaban exposure and an increased risk of bleeding Details Betrixaban Bemiparin Increased risk of bleeding Details Betrixaban Berotralstat Orladeyo Increased P-gp substrate exposure Details Betrixaban Bivalirudin Angiomax Increased risk of bleeding Details Betrixaban Bromfenac Bromsite An increased risk of bleeding Details Betrixaban Bufexamac An increased risk of bleeding Details Betrixaban Cangrelor Kengreal Increased risk of bleeding Details Betrixaban Caplacizumab-Yhdp An increased risk of bleeding Details Betrixaban Capmatinib Tabrecta Increased P-gp substrate exposure and an increased risk of increased adverse reactions Details Betrixaban Carbamazepine Carbatrol Decreased betrixaban exposure Details Betrixaban Carvedilol Coreg Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Celecoxib Celebrex An increased risk of bleeding Details Betrixaban Certoparin Increased risk of bleeding Details Betrixaban Choline Salicylate An increased risk of bleeding Details Betrixaban Cilostazol Pletal® Increased risk of bleeding Details Betrixaban Citalopram Celexa An increased risk of bleeding Details Betrixaban Clarithromycin Biaxin Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Clonixin An increased risk of bleeding Details Betrixaban Clopidogrel Plavix Increased risk of bleeding Details Betrixaban Cobicistat Tybost Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Conivaptan Vaprisol Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Curcumin An increased risk of bleeding Details Betrixaban Cyclosporine Atopica Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Dabigatran Etexilate Increased risk of bleeding Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.