Betrixaban

207 interactions 1 explained in plain English 188 cited references

Also sold as: Bevyxxa®

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Venlafaxine Omadacycline Injection Verapamil Venetoclax Vorapaxar Vimseltinib

202 Major 5 Moderate

All (207) Major (202) Moderate (5)

Major

Betrixaban Dalteparin Fragmin Increased risk of bleeding Details Betrixaban Danaparoid Increased risk of bleeding Details Betrixaban Defibrotide Increased risk of bleeding Details Betrixaban Desirudin Iprivask Increased risk of bleeding Details Betrixaban Desvenlafaxine Pristiq An increased risk of bleeding Details Betrixaban Dexibuprofen An increased risk of bleeding Details Betrixaban Dexketoprofen An increased risk of bleeding Details Betrixaban Diclofenac Aleve Arthritis Pain An increased risk of bleeding Details Betrixaban Diflunisal Dolobid An increased risk of bleeding Details Betrixaban Dipyridamole Permole® Increased risk of bleeding Details Betrixaban Dipyrone An increased risk of bleeding Details Betrixaban Donanemab-Azbt An increased risk of amyloid related imaging abnormalities (ARIA), or intracerebral hemorrhage Details Betrixaban Doxycycline Acticlate An increased risk of bleeding Details Betrixaban Dronedarone Multaq Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Drotrecogin Alfa Increased risk of bleeding Details Betrixaban Droxicam An increased risk of bleeding Details Betrixaban Duloxetine An increased risk of bleeding Details Betrixaban Edoxaban Savaysa Increased risk of bleeding Details Betrixaban Enoxaparin Lovenox Increased risk of bleeding Details Betrixaban Ensitrelvir Increased risk of P-gp substrate exposure Details Betrixaban Epoprostenol Flolan Increased risk of bleeding Details Betrixaban Eptifibatide Increased risk of bleeding Details Betrixaban Erythromycin Erythrocin Stearate Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Escitalopram Lexapro An increased risk of bleeding Details Betrixaban Etodolac Lodine An increased risk of bleeding Details Betrixaban Etofenamate An increased risk of bleeding Details Betrixaban Etoricoxib An increased risk of bleeding Details Betrixaban Felbinac An increased risk of bleeding Details Betrixaban Fenoprofen Fenopron An increased risk of bleeding Details Betrixaban Fepradinol An increased risk of bleeding Details Betrixaban Feprazone An increased risk of bleeding Details Betrixaban Flibanserin Addyi Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Floctafenine An increased risk of bleeding Details Betrixaban Flufenamic Acid An increased risk of bleeding Details Betrixaban Fluoxetine RECONCILE An increased risk of bleeding Details Betrixaban Flurbiprofen Ansaid An increased risk of bleeding Details Betrixaban Fluvoxamine An increased risk of bleeding Details Betrixaban Fondaparinux Arixtra Increased risk of bleeding Details Betrixaban Fosphenytoin Cerebyx Decreased betrixaban exposure Details Betrixaban Garlic Increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.