Betrixaban

207 interactions 1 explained in plain English 188 cited references

Also sold as: Bevyxxa®

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Venlafaxine Omadacycline Injection Verapamil Venetoclax Vorapaxar Vimseltinib

202 Major 5 Moderate

All (207) Major (202) Moderate (5)

Major

Betrixaban Ginkgo Increased risk of bleeding Details Betrixaban Heparin Increased risk of bleeding Details Betrixaban Ibuprofen Addaprin An increased risk of bleeding Details Betrixaban Iloprost Aurlumyn Increased risk of bleeding Details Betrixaban Indomethacin Indocin An increased risk of bleeding Details Betrixaban Inotersen Increased risk of bleeding Details Betrixaban Itraconazole Sporanox Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Ketoconazole Extina Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Ketoprofen Actron® An increased risk of bleeding Details Betrixaban Ketorolac Acular An increased risk of bleeding Details Betrixaban Lapatinib Tykerb Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Lecanemab-Irmb An increased risk of amyloid related imaging abnormalities (ARIA), or intracerebral hemorrhage Details Betrixaban Lenacapavir Sunlenca Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse reactions Details Betrixaban Lepirudin Increased risk of bleeding Details Betrixaban Levomilnacipran An increased risk of bleeding Details Betrixaban Lornoxicam An increased risk of bleeding Details Betrixaban Loxoprofen An increased risk of bleeding Details Betrixaban Lumiracoxib An increased risk of bleeding Details Betrixaban Meclofenamate Meclodium® An increased risk of bleeding Details Betrixaban Mefenamic Acid Ponstel® An increased risk of bleeding Details Betrixaban Meloxicam Alloxate An increased risk of bleeding Details Betrixaban Milnacipran Savella An increased risk of bleeding Details Betrixaban Minocycline Amzeeq An increased risk of bleeding Details Betrixaban Morniflumate An increased risk of bleeding Details Betrixaban Nabumetone Relafen An increased risk of bleeding Details Betrixaban Nadroparin Increased risk of bleeding Details Betrixaban Naproxen Aleve An increased risk of bleeding Details Betrixaban Nepafenac Ilevro An increased risk of bleeding Details Betrixaban Niflumic Acid An increased risk of bleeding Details Betrixaban Nimesulide An increased risk of bleeding Details Betrixaban Nimesulide Beta Cyclodextrin An increased risk of bleeding Details Betrixaban Omadacycline Nuzyra Increased risk of bleeding Details Betrixaban Orlistat Alli An increased risk of bleeding Details Betrixaban Oxaprozin Coxanto An increased risk of bleeding Details Betrixaban Oxyphenbutazone An increased risk of bleeding Details Betrixaban Parecoxib An increased risk of bleeding Details Betrixaban Parnaparin Increased risk of bleeding Details Betrixaban Paroxetine Paxil An increased risk of bleeding Details Betrixaban Phenindione Increased risk of bleeding Details Betrixaban Phenprocoumon Increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.