Betrixaban

207 interactions 1 explained in plain English 188 cited references

Also sold as: Bevyxxa®

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Venlafaxine Omadacycline Injection Verapamil Venetoclax Vorapaxar Vimseltinib

202 Major 5 Moderate

All (207) Major (202) Moderate (5)

Major

Betrixaban Phenylbutazone Equi-Phar An increased risk of bleeding Details Betrixaban Phenytoin Dilantin Decreased betrixaban exposure Details Betrixaban Piketoprofen An increased risk of bleeding Details Betrixaban Piperacillin An increased risk of bleeding Details Betrixaban Piroxicam Feldene An increased risk of bleeding Details Betrixaban Pranoprofen An increased risk of bleeding Details Betrixaban Prasugrel Effient Increased risk of bleeding Details Betrixaban Proglumetacin An increased risk of bleeding Details Betrixaban Propyphenazone An increased risk of bleeding Details Betrixaban Proquazone An increased risk of bleeding Details Betrixaban Protein C Ceprotin Increased risk of bleeding Details Betrixaban Quinidine Cardioquin® Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Ranolazine Aspruzyo Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Remibrutinib Rhapsido An increased risk of bleeding Details Betrixaban Reviparin Increased risk of bleeding Details Betrixaban Rifampin Rifadin Decreased betrixaban exposure Details Betrixaban Ritonavir Norvir Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Rivaroxaban Xarelto Increased risk of bleeding Details Betrixaban Rofecoxib An increased risk of bleeding Details Betrixaban Salicylic Acid An increased risk of bleeding Details Betrixaban Salsalate Disalcid An increased risk of bleeding Details Betrixaban Sarecycline Seysara Increased risk of bleeding Details Betrixaban Sodium Salicylate An increased risk of bleeding Details Betrixaban St John's Wort Decreased betrixaban exposure Details Betrixaban Streptokinase Increased risk of bleeding Details Betrixaban Sulfinpyrazone Increased risk of bleeding Details Betrixaban Sulindac Clinoril® An increased risk of bleeding Details Betrixaban Sulodexide Increased risk of bleeding Details Betrixaban Tazobactam An increased risk of bleeding Details Betrixaban Telaprevir Increased betrixaban exposure and increased risk of bleeding Details Betrixaban Tenecteplase Increased risk of bleeding Details Betrixaban Tenoxicam An increased risk of bleeding Details Betrixaban Tiaprofenic Acid An increased risk of bleeding Details Betrixaban Ticagrelor Brilinta Increased risk of bleeding Details Betrixaban Ticlopidine Ticlid® Increased risk of bleeding Details Betrixaban Tinzaparin Increased risk of bleeding Details Betrixaban Tipranavir Aptivus Decreased betrixaban exposure Details Betrixaban Tirofiban Increased risk of bleeding Details Betrixaban Tolfenamic Acid An increased risk of bleeding Details Betrixaban Tolmetin Tolectin 600 An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.