Bromfenac
86 interactions 5 explained in plain English
Also sold as:
Bromsite
Prolensa
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Ketorolac
Ketorolac Nasal Spray
Ketorolac Injection
Ketorolac Ophthalmic
Pemetrexed Injection
Deflazacort
Contraindicated
Bromfenac Ketorolac Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Bromfenac Ketorolac Injection Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Bromfenac Ketorolac Nasal Spray Sprix Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Bromfenac Ketorolac Ophthalmic Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) DetailsMajor
Bromfenac Amitriptyline Elavil Explained An increased risk of bleeding Details Bromfenac Sertraline Explained An increased risk of bleeding Details Bromfenac Apixaban Eliquis Explained An increased risk of bleeding Details Bromfenac Aspirin Acuprin® An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Bromfenac Aspirin Rectal Aspirin An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Bromfenac Betrixaban Bevyxxa® An increased risk of bleeding Details Bromfenac Anagrelide Agrylin An increased risk of bleeding Details Bromfenac Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Bromfenac Budesonide Nasal Spray Rhinocort Increased risk of gastrointestinal ulcer or bleeding Details Bromfenac Budesonide Oral Inhalation Pulmicort Increased risk of gastrointestinal ulcer or bleeding Details Bromfenac Clopidogrel Plavix An increased risk of bleeding Details Bromfenac Cyclosporine Injection Atopica An increased risk of cycloSPORINE nephrotoxicity Details Bromfenac Cyclosporine Ophthalmic Cequa An increased risk of cycloSPORINE nephrotoxicity Details Bromfenac Dabigatran Pradaxa® An increased risk of bleeding Details Bromfenac Dabigatran Etexilate An increased risk of bleeding Details Bromfenac Dalteparin Injection Fragmin An increased risk of bleeding Details Bromfenac Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Bromfenac Dexamethasone Injection Decadron Increased risk of gastrointestinal ulcer or bleeding Details Bromfenac Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of gastrointestinal ulcer or bleeding Details Bromfenac Digoxin Cardoxin® Increased digoxin exposure and prolonged half-life of digoxin Details Bromfenac Dipyridamole Permole® An increased risk of bleeding Details Bromfenac Edoxaban Savaysa An increased risk of bleeding Details Bromfenac Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Bromfenac Enoxaparin Lovenox An increased risk of bleeding Details Bromfenac Enoxaparin Injection Lovenox An increased risk of bleeding Details Bromfenac Epoprostenol Flolan An increased risk of bleeding Details Bromfenac Etodolac Lodine Increased risk of bleeding Details Bromfenac Fenoprofen Fenopron Increased risk of bleeding Details Bromfenac Flurbiprofen Ansaid Increased risk of bleeding Details Bromfenac Flurbiprofen Ophthalmic Ocufen Increased risk of bleeding Details Bromfenac Fondaparinux Arixtra An increased risk of bleeding Details Bromfenac Fondaparinux Injection Arixtra An increased risk of bleeding Details Bromfenac Furosemide Injection Disal Reduced diuretic effectiveness and possible nephrotoxicity Details Bromfenac Heparin An increased risk of bleeding Details Bromfenac Heparin Injection Lipo-Hepin® An increased risk of bleeding Details Bromfenac Hydrocortisone Ala-Cort Increased risk of gastrointestinal ulcer or bleeding DetailsNo interactions on this page match that filter — try the next page or clear the filter.
Check another drug
Still have questions about this combination?
Every question gets a real answer from a licensed pharmacist — free, and usually within a day.
Ask the pharmacistEducational information only, not medical advice. Always confirm interactions with your pharmacist
or prescriber before making any change to your medications.