Budesonide

248 interactions 1 explained in plain English 609 cited references

Also sold as: Entocort Entocort® EC Eohilia Ortikos Pulmicort Rhinocort Tarpeyo Tarpeyo ® Uceris

About Budesonide

Budesonide is a corticosteroid used to treat Crohn's disease and reduce protein in urine from kidney disease. Read the full Budesonide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Ensitrelvir Levoketoconazole Desmopressin Desmopressin Nasal Ofloxacin Otic

5 Contraindicated 202 Major 41 Moderate

All (248) Contraindicated (5) Major (202) Moderate (41)

Major

Budesonide Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Budesonide Aspirin Rectal Aspirin An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Budesonide Besifloxacin Ophthalmic Besivance An increased risk of tendon rupture Details Budesonide Bromfenac Ophthalmic Bromday® Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Aceclofenac Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Acemetacin Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Adagrasib Krazati Increased CYP3A4 substrate exposure Details Budesonide Amiodarone Nexterone Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Budesonide Amprenavir Increased budesonide exposure Details Budesonide Amtolmetin Guacil Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Apalutamide Erleada Reduced CYP3A4 substrate exposure Details Budesonide Aprepitant Aponvie Increased budesonide exposure Details Budesonide Atazanavir Reyataz Increased budesonide exposure Details Budesonide Avacopan Tavneos Increased budesonide exposure Details Budesonide Balofloxacin An increased risk of tendon rupture Details Budesonide Bemiparin Increased risk of bleeding Details Budesonide Berotralstat Orladeyo Increased budesonide exposure Details Budesonide Besifloxacin An increased risk of tendon rupture Details Budesonide Boceprevir Increased budesonide exposure and significantly reduced serum cortisol concentrations Details Budesonide Bromfenac Bromsite Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Bufexamac Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Bupropion Aplenzin Lowering of the seizure threshold Details Budesonide Carbamazepine Carbatrol Reduced corticosteroids exposure and reduced efficacy of corticosteroids Details Budesonide Celecoxib Celebrex Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Ceritinib Zykadia Increased CYP3A substrate exposure Details Budesonide Choline Salicylate Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Cilostazol Pletal® Increased budesonide exposure Details Budesonide Cimetidine Tagamet Increased budesonide exposure Details Budesonide Ciprofloxacin An increased risk of tendon rupture Details Budesonide Clarithromycin Biaxin Increased budesonide exposure Details Budesonide Clofazimine Increased budesonide exposure Details Budesonide Clonixin Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Cobicistat Tybost Increased budesonide exposure and increased risk for systemic corticosteroid effects Details Budesonide Conivaptan Vaprisol Increased CYP3A substrate exposure Details Budesonide Cosyntropin False elevations of plasma cortisol levels Details Budesonide Cyclosporine Atopica Increased budesonide exposure Details Budesonide Dabrafenib Tafinlar Reduced sensitive CYP3A4 substrate exposure Details Budesonide Darunavir Increased corticosteroid exposure Details Budesonide Delavirdine Rescriptor® Increased budesonide exposure Details Budesonide Dexibuprofen Increased risk of gastrointestinal ulcer or bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.