Budesonide

248 interactions 1 explained in plain English 609 cited references

Also sold as: Entocort Entocort® EC Eohilia Ortikos Pulmicort Rhinocort Tarpeyo Tarpeyo ® Uceris

About Budesonide

Budesonide is a corticosteroid used to treat Crohn's disease and reduce protein in urine from kidney disease. Read the full Budesonide drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Ensitrelvir Levoketoconazole Desmopressin Desmopressin Nasal Ofloxacin Otic

5 Contraindicated 202 Major 41 Moderate

All (248) Contraindicated (5) Major (202) Moderate (41)

Major

Budesonide Nimesulide Beta Cyclodextrin Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Nirmatrelvir Increased corticosteroid exposure Details Budesonide Norfloxacin An increased risk of tendon rupture Details Budesonide Ofloxacin Floxin® An increased risk of tendon rupture Details Budesonide Olutasidenib Rezlidhia Reduced sensitive CYP3A substrate exposure Details Budesonide Omaveloxolone Skyclarys Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Budesonide Oxaprozin Coxanto Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Oxyphenbutazone Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Palbociclib Ibrance Increased budesonide exposure Details Budesonide Parecoxib Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Paritaprevir Increased budesonide exposure Details Budesonide Pazufloxacin An increased risk of tendon rupture Details Budesonide Pefloxacin An increased risk of tendon rupture Details Budesonide Phenobarbital Fidoquel Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Budesonide Phenylbutazone Equi-Phar Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Phenytoin Dilantin Reduced corticosteroid exposure Details Budesonide Piketoprofen Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Piroxicam Feldene Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Pirtobrutinib Jaypirca Increased sensitive CYP3A substrate exposure and an increased risk of sensitive CYP3A substrate-related adverse effects Details Budesonide Posaconazole Noxafil Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Budesonide Pranoprofen Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Primidone Mysoline Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Budesonide Proglumetacin Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Propyphenazone Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Proquazone Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Prulifloxacin An increased risk of tendon rupture Details Budesonide Ranitidine Increased budesonide exposure Details Budesonide Ranolazine Aspruzyo Increased exposure of CYP3A4 substrate Details Budesonide Relacorilant Lifyorli Reduced relacorilant exposure and reduced efficacy of relacorilant, altered (reduced/increased) glucocorticoids exposure, reduced... Details Budesonide Ribociclib Kisqali Increased budesonide exposure Details Budesonide Ritlecitinib Litfulo Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Budesonide Ritonavir Norvir Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Budesonide Rofecoxib Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Rufloxacin An increased risk of tendon rupture Details Budesonide Salicylic Acid Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Salsalate Disalcid Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Saquinavir Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Budesonide Sargramostim Leukine Increased myeloproliferative effects of sargramostim Details Budesonide Schisandra Sphenanthera Increased budesonide exposure Details Budesonide Sodium Salicylate Increased risk of gastrointestinal ulcer or bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.