Budesonide

248 interactions 1 explained in plain English 609 cited references
Also sold as: Entocort Entocort® EC Eohilia Ortikos Pulmicort Rhinocort Tarpeyo Tarpeyo ® Uceris
About Budesonide

Budesonide is a corticosteroid used to treat Crohn's disease and reduce protein in urine from kidney disease. Read the full Budesonide drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Ensitrelvir Levoketoconazole Desmopressin Desmopressin Nasal Ofloxacin Otic
5 Contraindicated 202 Major 41 Moderate
All (248) Contraindicated (5) Major (202) Moderate (41)

Major

Budesonide Somatrogon-Ghla Reduced serum cortisol exposure, an increased risk of central (secondary) hypoadrenalism and attenuated growth-promoting effects o... Details Budesonide Sparfloxacin An increased risk of tendon rupture Details Budesonide Sulindac Clinoril® Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Suzetrigine Journavx Reduced sensitive CYP3A substrate exposure and reduced efficacy of sensitive CYP3A substrate Details Budesonide Tazemetostat Tazverik Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Budesonide Telaprevir Increased budesonide exposure and significantly reduced serum cortisol concentrations Details Budesonide Telithromycin Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Budesonide Tenoxicam Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Tiaprofenic Acid Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Tolfenamic Acid Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Tolmetin Tolectin 600 Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Tosufloxacin An increased risk of tendon rupture Details Budesonide Trofinetide Daybue Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related toxicities Details Budesonide Troleandomycin Increased budesonide exposure Details Budesonide Tucatinib Tukysa Increased budesonide exposure Details Budesonide Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details Budesonide Valdecoxib Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Verapamil Calan Increased budesonide exposure Details Budesonide Vonoprazan Voquezna Increased budesonide exposure Details Budesonide Voriconazole Vfend Increased budesonide exposure, an increased risk of Cushing's syndrome and an increased risk of adrenal dysfunction Details Budesonide Voxelotor Oxbryta Increased budesonide exposure Details Budesonide Cyclosporine Injection Atopica Increased budesonide exposure Details Budesonide Cyclosporine Ophthalmic Cequa Increased budesonide exposure Details Budesonide Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Diclofenac Transdermal Patch Flector Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Flurbiprofen Ophthalmic Ocufen Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Gatifloxacin Ophthalmic Zymar® An increased risk of tendon rupture Details Budesonide Ketoconazole Topical Extina® Foam Increased budesonide exposure Details Budesonide Ketorolac Injection Acular Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Ketorolac Nasal Spray Sprix Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Ketorolac Ophthalmic Acular Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Lenacapavir Injection Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of Cushing's syndrome and adrenal suppression Details Budesonide Lenacapavir Oral Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of Cushing's syndrome and adrenal suppression Details Budesonide Letermovir Injection Prevymis Increased budesonide exposure Details Budesonide Levofloxacin Injection Levaquin An increased risk of tendon rupture Details Budesonide Meloxicam Injection Alloxate Increased risk of gastrointestinal ulcer or bleeding Details Budesonide Moxifloxacin Injection Avelox An increased risk of tendon rupture Details Budesonide Moxifloxacin Ophthalmic Moxeza® An increased risk of tendon rupture Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.