Clindamycin

Name: Clindamycin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

84 interactions 71 explained in plain English 678 cited references

Also sold as: ANTIROBE Cleocin Cleocin-T Cleocin® Clinda-Guard Clindacin ClindaCure Clindagel Clindamax Clindesse Clintabs Evoclin Xaciato Zydaclin

About Clindamycin

Clindamycin is a lincomycin antibiotic used to treat bacterial infections of the lungs, skin, blood, and internal organs. Read the full Clindamycin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 2, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Levoketoconazole Apalutamide Asciminib Octreotide Injection Lanreotide Injection

2 Contraindicated 61 Major 21 Moderate

All (84) Contraindicated (2) Major (61) Moderate (21)

Moderate

Clindamycin Vecuronium Explained Vecuronium toxicity (respiratory depression) Details Clindamycin Cyclosporine Injection Atopica Decreased cycloSPORINE bioavailability Details Clindamycin Cyclosporine Ophthalmic Cequa Decreased cycloSPORINE bioavailability Details Clindamycin Lixisenatide Injection Adlyxin® Delayed therapeutic effect Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.