Degarelix

62 interactions 4 explained in plain English
Also sold as: Firmagon
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Amitriptyline Gatifloxacin Ophthalmic Buprenorphine Relugolix Ketoconazole Topical Foscarnet Injection
62 Major
All (62) Major (62)

Major

Degarelix Ketoconazole Topical Extina® Foam Increased risk of QT interval prolongation Details Degarelix Lefamulin Xenleta Increased risk of QT interval prolongation Details Degarelix Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Degarelix Levofloxacin Levaquin Increased risk of QT interval prolongation Details Degarelix Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Degarelix Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Degarelix Mefloquine Lariam® Increased risk of QT interval prolongation Details Degarelix Metronidazole Flagyl Increased risk of QT interval prolongation Details Degarelix Metronidazole Injection Flagyl Increased risk of QT interval prolongation Details Degarelix Metronidazole Topical MetroCream® Increased risk of QT interval prolongation Details Degarelix Metronidazole Vaginal MetroGel® Vaginal Increased risk of QT interval prolongation Details Degarelix Moxifloxacin Avelox Increased risk of QT interval prolongation Details Degarelix Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Degarelix Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Degarelix Nafarelin Nasal Spray Synarel Increased risk of QT interval prolongation Details Degarelix Octreotide Bynfezia Increased risk of QT interval prolongation Details Degarelix Octreotide Injection Bynfezia Increased risk of QT interval prolongation Details Degarelix Ofloxacin Floxin® Increased risk of QT interval prolongation Details Degarelix Ofloxacin Ophthalmic Ocuflox Increased risk of QT interval prolongation Details Degarelix Ofloxacin Otic Floxin® Otic Increased risk of QT interval prolongation Details Degarelix Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Degarelix Oxaliplatin Injection Eloxatin® Increased risk of QT-interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.