Delafloxacin

Name: Delafloxacin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

52 interactions 27 cited references

Also sold as: Baxdela Baxdela®

About Delafloxacin

Delafloxacin is used to treat skin infections and certain types of pneumonia (an infection of the lungs) caused by bacteria in adults. Delafloxacin is in a class of antibiotics called fluoroquinolones. It works by killing the bacteria that cause infections. Antibiotics such as delafloxacin will not work for colds, flu,… Read the full Delafloxacin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acarbose Lixisenatide Injection Dulaglutide Injection Dapagliflozin Insulin Detemir (Rdna Origin) Injection Liraglutide Injection

46 Major 6 Moderate

All (52) Major (46) Moderate (6)

Major

Delafloxacin Exenatide Injection Bydureon Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Insulin Detemir (Rdna Origin) Injection Levemir Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Insulin Glulisine (Rdna Origin) Injection Apidra Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Liraglutide Injection Saxenda Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Lixisenatide Injection Adlyxin® Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details

Moderate

Delafloxacin Aluminum Decreased delafloxacin efficacy Details Delafloxacin Calcium Decreased delafloxacin efficacy Details Delafloxacin Iron Decreased delafloxacin efficacy Details Delafloxacin Magnesium Decreased delafloxacin efficacy Details Delafloxacin Sucralfate Carafate Decreased delafloxacin efficacy Details Delafloxacin Zinc Decreased delafloxacin efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.