Desflurane

76 interactions 5 explained in plain English

Also sold as: Suprane

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Amitriptyline Gatifloxacin Ophthalmic Buprenorphine Relugolix Ketoconazole Topical Foscarnet Injection

68 Major 8 Moderate

All (76) Major (68) Moderate (8)

Major

Desflurane Inotuzumab Ozogamicin Injection Besponsa An increased risk of QT interval prolongation Details Desflurane Ivabradine Corlanor An increased risk of QT interval prolongation Details Desflurane Ketoconazole Topical Extina® Foam An increased risk of QT interval prolongation Details Desflurane Lefamulin Xenleta An increased risk of QT interval prolongation Details Desflurane Lenvatinib Lenvima An increased risk of QT interval prolongation Details Desflurane Levofloxacin Levaquin An increased risk of QT interval prolongation Details Desflurane Levofloxacin Injection Levaquin An increased risk of QT interval prolongation Details Desflurane Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Desflurane Mefloquine Lariam® An increased risk of QT interval prolongation Details Desflurane Methylphenidate Adhansia XR® Increased risk of sudden blood pressure and heart rate increases Details Desflurane Methylphenidate Transdermal Patch Daytrana Increased risk of sudden blood pressure and heart rate increases Details Desflurane Metronidazole Flagyl An increased risk of QT interval prolongation Details Desflurane Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Desflurane Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Desflurane Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Desflurane Midazolam Nasal Spray Nayzilam Reduced desflurane (MAC) exposure needed to produce anesthesia Details Desflurane Midazolam Injection Nayzilam Reduced desflurane (MAC) exposure needed to produce anesthesia Details Desflurane Moxifloxacin Avelox An increased risk of QT interval prolongation Details Desflurane Moxifloxacin Injection Avelox An increased risk of QT interval prolongation Details Desflurane Moxifloxacin Ophthalmic Moxeza® An increased risk of QT interval prolongation Details Desflurane Nafarelin Nasal Spray Synarel An increased risk of QT interval prolongation Details Desflurane Octreotide Bynfezia An increased risk of QT interval prolongation Details Desflurane Octreotide Injection Bynfezia An increased risk of QT interval prolongation Details Desflurane Ofloxacin Floxin® An increased risk of QT interval prolongation Details Desflurane Ofloxacin Ophthalmic Ocuflox An increased risk of QT interval prolongation Details Desflurane Ofloxacin Otic Floxin® Otic An increased risk of QT interval prolongation Details Desflurane Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details Desflurane Oxaliplatin Injection Eloxatin® An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.