Deuruxolitinib

Name: Deuruxolitinib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

50 interactions 21 cited references

Read the full Deuruxolitinib drug information page

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Miconazole Vaginal Adagrasib Miconazole Fluconazole Amiodarone Ensitrelvir

13 Contraindicated 31 Major 6 Moderate

All (50) Contraindicated (13) Major (31) Moderate (6)

Major

Deuruxolitinib Yellow Fever Vaccine Stamaril An increased risk of drug-drug interactions Details Deuruxolitinib Zoster Vaccine, Live An increased risk of drug-drug interactions Details Deuruxolitinib Fluorouracil Injection Adrucil Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Deuruxolitinib Fluorouracil Topical Carac Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details

Moderate

Deuruxolitinib Artemether Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Deuruxolitinib Kratom Increased CYP3A substrate exposure Details Deuruxolitinib Levothyroxine Ermeza Increased risk of hypothyroidism Details Deuruxolitinib Mavacamten Camzyos Reduced CYP3A4/CYP2C9 substrate exposure and reduced efficacy of CYP3A4/CYP2C9 substrate Details Deuruxolitinib Rilzabrutinib Wayrilz Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Deuruxolitinib Sparsentan Filspari Reduced CYP2C9 substrate exposure and reduced efficacy of CYP2C9 substrate Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.