Elacestrant

Name: Elacestrant Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

123 interactions 283 cited references

Also sold as: Orserdu Orserdu®

About Elacestrant

Elacestrant is used to treat certain types of hormone receptor-positive breast cancer (breast cancer that depends on hormones such as estrogen to grow) in adults who have had disease progression following treatment with at least one other hormone therapies. Elacestrant is in a class of medications called estrogen recep… Read the full Elacestrant drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mumps Virus Vaccine, Live Bacillus Of Calmette And Guerin Vaccine, Live Levoketoconazole Ensitrelvir Measles Virus Vaccine, Live Dengue Tetravalent Vaccine, Live

11 Contraindicated 106 Major 6 Moderate

All (123) Contraindicated (11) Major (106) Moderate (6)

Moderate

Elacestrant Rilzabrutinib Wayrilz Increased CYP3A substrate exposure and an increased risk of CYP3A substrate-related adverse reactions Details Elacestrant Tenofovir Alafenamide Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details Elacestrant Tenofovir Disoproxil Fumarate Increased tenofovir alafenamide or tenofovir disoproxil fumarate exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.