Epirubicin and Tasonermin: Interaction Details
AI-assisted, pharmacist-reviewed · Source data updated Aug 8, 2026 · Sources: FDA labeling, DDInter 2.0, cited literature
Epirubicin
Tasonermin
No brand names on record
How we grade severity & evidence
Severity levels
- Contraindicated: These should generally not be used together.
- Major: Potentially serious — often needs a change or close monitoring.
- Moderate: Can be significant — usually manageable with monitoring.
- Minor: Usually limited clinical impact.
Evidence grades
- Established: Well documented — supported by controlled studies or strong clinical data.
- Probable: Good supporting evidence, though not definitively proven.
- Suspected: Some evidence suggests this interaction, but it is not well established.
- Possible: Limited or conflicting evidence; the interaction may occur.
- Theoretical: Predicted from the drugs' pharmacology; not yet confirmed in people.
Ratings come from the documented interaction literature and are reviewed by a pharmacist. They describe the documented risk of the combination, not what will necessarily happen to you — your dose, timing, and health picture all matter.
What happens
Increased risk of cardiotoxicity
Interaction Deep Dive
Concomitant use of tasonermin and cardiotoxic agents such as anthracyclines is contraindicated as enhanced cardiotoxicity has been reported in preclinical 13-week toxicological investigations1.
Why it happens (mechanism)
Additive cardiotoxicity
Common questions
Can I take Epirubicin and Tasonermin together?
Increased risk of cardiotoxicity Always confirm with your pharmacist or prescriber before making any change.
How serious is the Epirubicin and Tasonermin interaction?
It is rated contraindicated. These should generally not be used together.
How quickly could this interaction happen?
The documented onset is "unspecified". The timing of this interaction is not well characterized.
How strong is the evidence for this interaction?
The evidence is graded "theoretical". Predicted from the drugs' pharmacology; not yet confirmed in people.
Questions for your pharmacist
- Does my dose of Epirubicin or Tasonermin need adjusting while I take them together?
- What symptoms should prompt me to call you or my prescriber right away?
- Does the timing of my doses matter for this combination?
- Is there a safer alternative to one of these medications for me?
References (1)
- Product Information: Beromun intraarterial injection powder for solution, tasonermin intraarterial injection powder for solution. Boehringer Ingelheim RCV GmbH & Co KG (per EMA), Vienna, Austria, 2014.
Keep reading about Epirubicin
Keep reading about Tasonermin
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