Fexinidazole

Major

Fexinidazole Budesonide Oral Inhalation Pulmicort An increased CYP3A4 substrate exposure Details Fexinidazole Cabozantinib Cabometyx An increased CYP3A4 substrate exposure Details Fexinidazole Cabozantinib (Thyroid Cancer) Cabometyx An increased CYP3A4 substrate exposure Details Fexinidazole Capmatinib Tabrecta An increased CYP3A4 substrate exposure Details Fexinidazole Chloroquine Aralen® An increased risk of QT interval prolongation Details Fexinidazole Cobimetinib Cotellic An increased CYP3A4 substrate exposure Details Fexinidazole Cyclophosphamide Cytoxan® Decreased plasma concentrations of CYP2B6 substrate Details Fexinidazole Cyclophosphamide Injection Cytoxan® Injection Decreased plasma concentrations of CYP2B6 substrate Details Fexinidazole Cyclosporine Injection Atopica Decreased exposure of active fexinidazole metabolites; potential decreased efficacy of fexinidazole; increased adverse effects of... Details Fexinidazole Cyclosporine Ophthalmic Cequa Decreased exposure of active fexinidazole metabolites; potential decreased efficacy of fexinidazole; increased adverse effects of... Details Fexinidazole Dalfampridine Ampyra Increased dalfampridine exposure Details Fexinidazole Darolutamide Nubeqa An increased CYP3A4 substrate exposure Details Fexinidazole Dasatinib Phyrago Increased exposure of CYP3A4 substrate; increased risk of QT interval prolongation and arrhythmias Details Fexinidazole Degarelix Injection Firmagon An increased risk of QT interval prolongation Details Fexinidazole Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Fexinidazole Dexamethasone Injection Decadron Increased exposure of fexinidazole metabolites with possible increased risk of QT prolongation; increased exposure of CYP3A4 subst... Details Fexinidazole Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased exposure of fexinidazole metabolites with possible increased risk of QT prolongation; increased exposure of CYP3A4 subst... Details Fexinidazole Diazepam Nasal Spray Valtoco An increased CYP3A4 substrate exposure Details Fexinidazole Diazepam Rectal Diastat An increased CYP3A4 substrate exposure Details Fexinidazole Dihydroergotamine Injection DHE-45® Injection An increased CYP3A4 substrate exposure Details Fexinidazole Dihydroergotamine Nasal Spray Migranal An increased CYP3A4 substrate exposure Details Fexinidazole Disopyramide Norpace An increased risk of QT interval prolongation Details Fexinidazole Disulfiram Antabuse CNS toxicity (psychotic symptoms) Details Fexinidazole Docetaxel Beizray An increased CYP3A4 substrate exposure Details Fexinidazole Docetaxel Injection Beizray An increased CYP3A4 substrate exposure Details Fexinidazole Dofetilide Tikosyn Increased dofetilide exposure and an increased risk of QT interval prolongation Details Fexinidazole Dolasetron Anzemet An increased risk of QT interval prolongation Details Fexinidazole Dolasetron Injection Anzemet An increased risk of QT interval prolongation Details Fexinidazole Dolutegravir Juluca® (as a combination product containing dolutegravir, rilpivirine) An increased CYP3A4 substrate exposure Details Fexinidazole Encorafenib Braftovi Increased risk of QT interval prolongation Details Fexinidazole Entrectinib Rozlytrek Increased exposure of CYP3A4 substrate; increased risk of QT interval prolongation and arrhythmias Details Fexinidazole Eravacycline Injection Xerava An increased CYP3A4 substrate exposure Details Fexinidazole Eribulin Injection Halaven An increased risk of QT interval prolongation Details Fexinidazole Esmolol Brevibloc Increased risk of bradycardia Details Fexinidazole Estradiol Delestrogen An increased CYP3A4 substrate exposure Details Fexinidazole Estradiol Topical Divigel An increased CYP3A4 substrate exposure Details Fexinidazole Estradiol Transdermal Patch Alora® An increased CYP3A4 substrate exposure Details Fexinidazole Everolimus Afinitor An increased CYP3A4 substrate exposure Details Fexinidazole Famotidine Calmicid An increased risk of QT interval prolongation Details Fexinidazole Famotidine Injection Calmicid An increased risk of QT interval prolongation Details