Fondaparinux

204 interactions 288 cited references

Also sold as: Arixtra

Read the full Fondaparinux drug information page

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Defibrotide Injection Sulindac St John's Wort Streptokinase Omadacycline Injection

2 Contraindicated 157 Major 43 Moderate 2 Minor

All (204) Contraindicated (2) Major (157) Moderate (43) Minor (2)

Major

Fondaparinux Celecoxib Celebrex An increased risk of bleeding Details Fondaparinux Chamomile Increased risk of bleeding Details Fondaparinux Choline Salicylate An increased risk of bleeding Details Fondaparinux Cilostazol Pletal® Increased risk of bleeding Details Fondaparinux Citalopram Celexa An increased risk of bleeding Details Fondaparinux Clonixin An increased risk of bleeding Details Fondaparinux Collagenase, Clostridium Histolyticum Increased risk of bleeding adverse effects Details Fondaparinux Curcumin An increased risk of bleeding Details Fondaparinux Dalteparin Fragmin Increased risk of bleeding Details Fondaparinux Danaparoid Increased risk of bleeding Details Fondaparinux Desvenlafaxine Pristiq An increased risk of bleeding Details Fondaparinux Dexibuprofen An increased risk of bleeding Details Fondaparinux Dexketoprofen An increased risk of bleeding Details Fondaparinux Diclofenac Aleve Arthritis Pain An increased risk of bleeding Details Fondaparinux Diflunisal Dolobid An increased risk of bleeding Details Fondaparinux Dipyrone An increased risk of bleeding Details Fondaparinux Donanemab-Azbt An increased risk of amyloid related imaging abnormalities (ARIA), or intracerebral hemorrhage Details Fondaparinux Doxycycline Acticlate An increased risk of bleeding Details Fondaparinux Drotrecogin Alfa Increased risk of bleeding Details Fondaparinux Droxicam An increased risk of bleeding Details Fondaparinux Eptifibatide Increased risk of bleeding Details Fondaparinux Escitalopram Lexapro An increased risk of bleeding Details Fondaparinux Etofenamate An increased risk of bleeding Details Fondaparinux Etoricoxib An increased risk of bleeding Details Fondaparinux Felbinac An increased risk of bleeding Details Fondaparinux Fepradinol An increased risk of bleeding Details Fondaparinux Feprazone An increased risk of bleeding Details Fondaparinux Floctafenine An increased risk of bleeding Details Fondaparinux Flufenamic Acid An increased risk of bleeding Details Fondaparinux Fluoxetine RECONCILE An increased risk of bleeding Details Fondaparinux Fluvoxamine An increased risk of bleeding Details Fondaparinux Garlic Increased risk of bleeding Details Fondaparinux Ginkgo Increased risk of bleeding Details Fondaparinux Heparin Increased risk of bleeding Details Fondaparinux Ibrutinib Imbruvica Increased risk of bleeding Details Fondaparinux Ibuprofen Addaprin An increased risk of bleeding Details Fondaparinux Iloprost Aurlumyn Increased risk of bleeding Details Fondaparinux Indomethacin Indocin An increased risk of bleeding Details Fondaparinux Inotersen Increased risk of bleeding Details Fondaparinux Ketoprofen Actron® An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.