Fondaparinux

204 interactions 288 cited references

Also sold as: Arixtra

Read the full Fondaparinux drug information page

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Defibrotide Injection Sulindac St John's Wort Streptokinase Omadacycline Injection

2 Contraindicated 157 Major 43 Moderate 2 Minor

All (204) Contraindicated (2) Major (157) Moderate (43) Minor (2)

Major

Fondaparinux Ketorolac Acular An increased risk of bleeding Details Fondaparinux Lecanemab-Irmb An increased risk of amyloid related imaging abnormalities (ARIA), or intracerebral hemorrhage Details Fondaparinux Levomilnacipran An increased risk of bleeding Details Fondaparinux Lornoxicam An increased risk of bleeding Details Fondaparinux Loxoprofen An increased risk of bleeding Details Fondaparinux Lumiracoxib An increased risk of bleeding Details Fondaparinux Meclofenamate Meclodium® An increased risk of bleeding Details Fondaparinux Mefenamic Acid Ponstel® An increased risk of bleeding Details Fondaparinux Meloxicam Alloxate An increased risk of bleeding Details Fondaparinux Milnacipran Savella An increased risk of bleeding Details Fondaparinux Minocycline Amzeeq An increased risk of bleeding Details Fondaparinux Morniflumate An increased risk of bleeding Details Fondaparinux Nabumetone Relafen An increased risk of bleeding Details Fondaparinux Nadroparin An increased risk of bleeding Details Fondaparinux Naproxen Aleve An increased risk of bleeding Details Fondaparinux Nepafenac Ilevro An increased risk of bleeding Details Fondaparinux Niflumic Acid An increased risk of bleeding Details Fondaparinux Nimesulide An increased risk of bleeding Details Fondaparinux Nimesulide Beta Cyclodextrin An increased risk of bleeding Details Fondaparinux Nintedanib Ofev Increased risk of bleeding Details Fondaparinux Omadacycline Nuzyra Increased risk of bleeding Details Fondaparinux Orlistat Alli An increased risk of bleeding Details Fondaparinux Oxaprozin Coxanto An increased risk of bleeding Details Fondaparinux Oxyphenbutazone An increased risk of bleeding Details Fondaparinux Papaya Increased risk of bleeding Details Fondaparinux Parecoxib Increased risk of bleeding Details Fondaparinux Paroxetine Paxil An increased risk of bleeding Details Fondaparinux Pentosan Polysulfate Sodium An increased risk of bleeding Details Fondaparinux Phenylbutazone Equi-Phar An increased risk of bleeding Details Fondaparinux Piketoprofen An increased risk of bleeding Details Fondaparinux Piperacillin An increased risk of bleeding Details Fondaparinux Piracetam Increased risk of bleeding Details Fondaparinux Piroxicam Feldene An increased risk of bleeding Details Fondaparinux Pranoprofen An increased risk of bleeding Details Fondaparinux Prasugrel Effient Increased risk of bleeding Details Fondaparinux Proglumetacin An increased risk of bleeding Details Fondaparinux Propyphenazone An increased risk of bleeding Details Fondaparinux Proquazone An increased risk of bleeding Details Fondaparinux Remibrutinib Rhapsido An increased risk of bleeding Details Fondaparinux Reteplase, Recombinant An increased risk of bleeding Details

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