Foscarnet Injection and Capreomycin: Interaction Details
AI-assisted, pharmacist-reviewed · Source data updated Aug 8, 2026 · Sources: FDA labeling, DDInter 2.0, cited literature
Foscarnet Injection
Capreomycin
No brand names on record
How we grade severity & evidence
Severity levels
- Contraindicated: These should generally not be used together.
- Major: Potentially serious — often needs a change or close monitoring.
- Moderate: Can be significant — usually manageable with monitoring.
- Minor: Usually limited clinical impact.
Evidence grades
- Established: Well documented — supported by controlled studies or strong clinical data.
- Probable: Good supporting evidence, though not definitively proven.
- Suspected: Some evidence suggests this interaction, but it is not well established.
- Possible: Limited or conflicting evidence; the interaction may occur.
- Theoretical: Predicted from the drugs' pharmacology; not yet confirmed in people.
Ratings come from the documented interaction literature and are reviewed by a pharmacist. They describe the documented risk of the combination, not what will necessarily happen to you — your dose, timing, and health picture all matter.
What happens
Nephrotoxicity
Interaction Deep Dive
Concomitant use of foscarnet with potentially nephrotoxic drugs can have additive nephrotoxic adverse effects and should be avoided, unless the potential benefits outweigh the risks1.
Why it happens (mechanism)
Additive nephrotoxicity
Common questions
Can I take Foscarnet Injection and Capreomycin together?
Nephrotoxicity Always confirm with your pharmacist or prescriber before making any change.
How serious is the Foscarnet Injection and Capreomycin interaction?
It is rated major. Potentially serious — often needs a change or close monitoring.
How quickly could this interaction happen?
The documented onset is "unspecified". The timing of this interaction is not well characterized.
How strong is the evidence for this interaction?
The evidence is graded "theoretical". Predicted from the drugs' pharmacology; not yet confirmed in people.
Questions for your pharmacist
- Does my dose of Foscarnet Injection or Capreomycin need adjusting while I take them together?
- What symptoms should prompt me to call you or my prescriber right away?
- Does the timing of my doses matter for this combination?
- Is there a safer alternative to one of these medications for me?
References (1)
- Product Information: FOSCAVIR(R) intravenous injection solution, foscarnet sodium intravenous injection solution. Hospira, Inc. (per DailyMed), Lake Forest, IL, 2014. DailyMed
Keep reading about Foscarnet Injection
Keep reading about Capreomycin
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Prescription drugs aren't the whole picture — herbal and dietary supplements can interact with them too. From the evidence-graded Natural Medicines database:
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